Investigation of Chemical Compositions and Biological Activities of <i>Mentha suaveolens</i> L. from Saudi Arabia
<i>Mentha</i> is an aromatic plant used since antiquity for its pharmaceutical virtues. The climate of Saudi Arabia favors the growth of aromatic plants including <i>Mentha suaveolens</i> L. The aim of this study is to analyze the volatile oils of different parts of fresh and...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-05-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/9/2949 |
| _version_ | 1797503601077125120 |
|---|---|
| author | Bashayr Aldogman Hallouma Bilel Shaima Mohamed Nabil Moustafa Khaled F. Elmassary Hazim M. Ali Faddaa Qayid Alotaibi Mohamed Hamza Mohamed A. Abdelgawad Ahmed H. El-Ghorab |
| author_facet | Bashayr Aldogman Hallouma Bilel Shaima Mohamed Nabil Moustafa Khaled F. Elmassary Hazim M. Ali Faddaa Qayid Alotaibi Mohamed Hamza Mohamed A. Abdelgawad Ahmed H. El-Ghorab |
| author_sort | Bashayr Aldogman |
| collection | DOAJ |
| description | <i>Mentha</i> is an aromatic plant used since antiquity for its pharmaceutical virtues. The climate of Saudi Arabia favors the growth of aromatic plants including <i>Mentha suaveolens</i> L. The aim of this study is to analyze the volatile oils of different parts of fresh and dried <i>Mentha suaveolens</i> L. grown in Saudi Arabia (Aljouf area) using Gas Chromatography/Mass Spectrometry (GC/MS) and Gas Chromatography Flame Ionization Detector (GC/FID) techniques, to recognize the effect of drying on chemical composition, then to evaluate the antioxidant and antifungal activities of different extracts. In total, 118 compounds were identified via GC/MS and GC/FID, in which carvone is the main volatile constituent (stems, leaves, whole plant 45–64%). This investigation deduces that <i>Mentha</i> belonged to the carvone chemotype. Then, the analysis of non-volatile constituents of fresh and dried <i>Mentha</i> was performed by HPLC. The main phenolic compound of fresh and dried <i>Mentha</i> for different parts was rosmarinic acid (ranging from 28,002.5 to 6558 µg/g). The ethanolic extract of fresh stem showed the highest antifungal activity (53% inhibition) compared with miconazole (60% inhibition) but the ethanoic extract of dry stem showed no activity. Additionally, all ethanolic extracts, whether for fresh or dry <i>Mentha</i>, have antioxidant activity more than 90% while the antioxidant activity of whole plant volatile oil is equal to 53.33%. This research shows that <i>M. suaveolens</i> L. could be applied to manufacture natural antioxidants, antifungal, and flavoring agents. |
| first_indexed | 2024-03-10T03:53:02Z |
| format | Article |
| id | doaj.art-c5aca137d09b400b8d8688130d1991f1 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T03:53:02Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-c5aca137d09b400b8d8688130d1991f12023-11-23T08:52:13ZengMDPI AGMolecules1420-30492022-05-01279294910.3390/molecules27092949Investigation of Chemical Compositions and Biological Activities of <i>Mentha suaveolens</i> L. from Saudi ArabiaBashayr Aldogman0Hallouma Bilel1Shaima Mohamed Nabil Moustafa2Khaled F. Elmassary3Hazim M. Ali4Faddaa Qayid Alotaibi5Mohamed Hamza6Mohamed A. Abdelgawad7Ahmed H. El-Ghorab8Department of Chemistry, College of Science, Jouf University, Sakaka 72341, Saudi ArabiaDepartment of Chemistry, College of Science, Jouf University, Sakaka 72341, Saudi ArabiaDepartment of Biology, College of Science, Jouf University, Sakaka 72341, Saudi ArabiaFlavour and Aroma Department, National Research Centre, Giza P.O. Box 12622, EgyptDepartment of Chemistry, College of Science, Jouf University, Sakaka 72341, Saudi ArabiaDepartment of Chemistry, College of Science, Jouf University, Sakaka 72341, Saudi ArabiaDepartment of Biology, College of Science, Jouf University, Sakaka 72341, Saudi ArabiaDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka 72341, Saudi ArabiaDepartment of Chemistry, College of Science, Jouf University, Sakaka 72341, Saudi Arabia<i>Mentha</i> is an aromatic plant used since antiquity for its pharmaceutical virtues. The climate of Saudi Arabia favors the growth of aromatic plants including <i>Mentha suaveolens</i> L. The aim of this study is to analyze the volatile oils of different parts of fresh and dried <i>Mentha suaveolens</i> L. grown in Saudi Arabia (Aljouf area) using Gas Chromatography/Mass Spectrometry (GC/MS) and Gas Chromatography Flame Ionization Detector (GC/FID) techniques, to recognize the effect of drying on chemical composition, then to evaluate the antioxidant and antifungal activities of different extracts. In total, 118 compounds were identified via GC/MS and GC/FID, in which carvone is the main volatile constituent (stems, leaves, whole plant 45–64%). This investigation deduces that <i>Mentha</i> belonged to the carvone chemotype. Then, the analysis of non-volatile constituents of fresh and dried <i>Mentha</i> was performed by HPLC. The main phenolic compound of fresh and dried <i>Mentha</i> for different parts was rosmarinic acid (ranging from 28,002.5 to 6558 µg/g). The ethanolic extract of fresh stem showed the highest antifungal activity (53% inhibition) compared with miconazole (60% inhibition) but the ethanoic extract of dry stem showed no activity. Additionally, all ethanolic extracts, whether for fresh or dry <i>Mentha</i>, have antioxidant activity more than 90% while the antioxidant activity of whole plant volatile oil is equal to 53.33%. This research shows that <i>M. suaveolens</i> L. could be applied to manufacture natural antioxidants, antifungal, and flavoring agents.https://www.mdpi.com/1420-3049/27/9/2949<i>Mentha suaveolens</i> L.carvonerosmarinic acidantioxidantantifungal activity |
| spellingShingle | Bashayr Aldogman Hallouma Bilel Shaima Mohamed Nabil Moustafa Khaled F. Elmassary Hazim M. Ali Faddaa Qayid Alotaibi Mohamed Hamza Mohamed A. Abdelgawad Ahmed H. El-Ghorab Investigation of Chemical Compositions and Biological Activities of <i>Mentha suaveolens</i> L. from Saudi Arabia Molecules <i>Mentha suaveolens</i> L. carvone rosmarinic acid antioxidant antifungal activity |
| title | Investigation of Chemical Compositions and Biological Activities of <i>Mentha suaveolens</i> L. from Saudi Arabia |
| title_full | Investigation of Chemical Compositions and Biological Activities of <i>Mentha suaveolens</i> L. from Saudi Arabia |
| title_fullStr | Investigation of Chemical Compositions and Biological Activities of <i>Mentha suaveolens</i> L. from Saudi Arabia |
| title_full_unstemmed | Investigation of Chemical Compositions and Biological Activities of <i>Mentha suaveolens</i> L. from Saudi Arabia |
| title_short | Investigation of Chemical Compositions and Biological Activities of <i>Mentha suaveolens</i> L. from Saudi Arabia |
| title_sort | investigation of chemical compositions and biological activities of i mentha suaveolens i l from saudi arabia |
| topic | <i>Mentha suaveolens</i> L. carvone rosmarinic acid antioxidant antifungal activity |
| url | https://www.mdpi.com/1420-3049/27/9/2949 |
| work_keys_str_mv | AT bashayraldogman investigationofchemicalcompositionsandbiologicalactivitiesofimenthasuaveolensilfromsaudiarabia AT halloumabilel investigationofchemicalcompositionsandbiologicalactivitiesofimenthasuaveolensilfromsaudiarabia AT shaimamohamednabilmoustafa investigationofchemicalcompositionsandbiologicalactivitiesofimenthasuaveolensilfromsaudiarabia AT khaledfelmassary investigationofchemicalcompositionsandbiologicalactivitiesofimenthasuaveolensilfromsaudiarabia AT hazimmali investigationofchemicalcompositionsandbiologicalactivitiesofimenthasuaveolensilfromsaudiarabia AT faddaaqayidalotaibi investigationofchemicalcompositionsandbiologicalactivitiesofimenthasuaveolensilfromsaudiarabia AT mohamedhamza investigationofchemicalcompositionsandbiologicalactivitiesofimenthasuaveolensilfromsaudiarabia AT mohamedaabdelgawad investigationofchemicalcompositionsandbiologicalactivitiesofimenthasuaveolensilfromsaudiarabia AT ahmedhelghorab investigationofchemicalcompositionsandbiologicalactivitiesofimenthasuaveolensilfromsaudiarabia |