Assessment of dopaminergic neuron degeneration in a C. elegans model of Parkinson’s disease

Assessment of dopaminergic neuron degeneration in a C. elegans model of Parkinson’s disease

Summary: Transgenic Caenorhabditis elegans that expresses the full-length wild-type human α-synuclein in dopaminergic neurons provides a well-established Parkinson’s disease (PD) nematode model. Here, we present a detailed protocol to monitor and dissect the molecular underpinnings of age-associated...

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Bibliographic Details
Main Authors: Konstantinos Palikaras, Tanima SenGupta, Hilde Nilsen, Nektarios Tavernarakis
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:STAR Protocols
Subjects:
Cell Biology
Model Organisms
Molecular Biology
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722001447

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