Integrated molecular analyses of an interferon-γ based subtype with regard to outcome, immune characteristics, and immunotherapy in bladder cancer and experimental verification

Integrated molecular analyses of an interferon-γ based subtype with regard to outcome, immune characteristics, and immunotherapy in bladder cancer and experimental verification

This study attempted to explore the role of interferon-γ related genes (IRGs) in the prognosis and immunotherapy of bladder cancer (BC). Based on data downloaded from public databases, molecular subtypes with different IRG expression patterns were determined via nonnegative matrix factorization clus...

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Bibliographic Details
Main Authors: Jirong Wang, Siyu Chen, Huabin Wang, Jinlong Cao, Xinpeng Fan, Jiangwei Man, Qingchao Li, Li Yang
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Immune checkpoint inhibitor therapy
TCGA
GEO
Bioinformatics
Tumor immune microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022033904

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