Serologic Detection of Middle East Respiratory Syndrome Coronavirus Functional Antibodies

Serologic Detection of Middle East Respiratory Syndrome Coronavirus Functional Antibodies

We developed and validated 2 species-independent protein-based assays to detect Middle East respiratory syndrome coronavirus functional antibodies that can block virus receptor-binding or sialic acid-attachment. Antibody levels measured in both assays correlated strongly with virus-neutralizing anti...

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Bibliographic Details
Main Authors: Nisreen M.A. Okba, Ivy Widjaja, Wentao Li, Corine H. GeurtsvanKessel, Elmoubasher A.B.A. Farag, Mohammed Al-Hajri, Wan Beom Park, Myoung-don Oh, Chantal B.E.M. Reusken, Marion P.G. Koopmans, Berend-Jan Bosch, Bart L. Haagmans
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2020-05-01
Series:Emerging Infectious Diseases
Subjects:
Middle East respiratory syndrome coronavirus
MERS
neutralization
hemagglutination
lumazine synthase
antibodies
Online Access:https://wwwnc.cdc.gov/eid/article/26/5/19-0921_article

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