A single-cell level comparison of human inner ear organoids with the human cochlea and vestibular organs
Summary: Inner ear disorders are among the most common congenital abnormalities; however, current tissue culture models lack the cell type diversity to study these disorders and normal otic development. Here, we demonstrate the robustness of human pluripotent stem cell-derived inner ear organoids (I...
Main Authors: | Wouter H. van der Valk, Edward S.A. van Beelen, Matthew R. Steinhart, Carl Nist-Lund, Daniel Osorio, John C.M.J. de Groot, Liang Sun, Peter Paul G. van Benthem, Karl R. Koehler, Heiko Locher |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124723006344 |
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