Obesity and Angiogenesis
Nowadays, high prevalence of obesity and its consequences is considered as a major health complication worldwide. Overweight increases risk of diseases such as hypertension, cardiovascular diseases, type 2 diabetes, certain types of cancer, gallstone, and osteoarthritis. Obesity is defined as growth...
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Format: | Article |
Language: | fas |
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Isfahan University of Medical Sciences
2012-03-01
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Series: | مجله دانشکده پزشکی اصفهان |
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Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/1663 |
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author | Zoya Tahergurabi Majid Khazaei |
author_facet | Zoya Tahergurabi Majid Khazaei |
author_sort | Zoya Tahergurabi |
collection | DOAJ |
description | Nowadays, high prevalence of obesity and its consequences is considered as a major health complication worldwide. Overweight increases risk of diseases such as hypertension, cardiovascular diseases, type 2 diabetes, certain types of cancer, gallstone, and osteoarthritis. Obesity is defined as growth of visceral white adipose tissue. On the other hand, in order to supply for metabolic needs of adipose tissue, depends on appropriate growth of blood vessels, either in number and/or in size (angiogenesis/arteriogenesis). Moreover, the very close interconnection between adipogenesis and angiogenesis has been considered in recent years. Therapeutic interventions for treating obesity by targeting vessels of adipose tissue illustrate a promising future. In this review, we discussed adipose tissue, important roles and functions of vessels in adipose tissue, obesity, and angiogenesis. We finally presented suggestions on how to use anti-angiogenesis agents for treatment of obesity as a novel approach. |
first_indexed | 2024-03-12T09:18:22Z |
format | Article |
id | doaj.art-c5bb1972fa584c28808a5556e3aa2354 |
institution | Directory Open Access Journal |
issn | 1027-7595 1735-854X |
language | fas |
last_indexed | 2024-03-12T09:18:22Z |
publishDate | 2012-03-01 |
publisher | Isfahan University of Medical Sciences |
record_format | Article |
series | مجله دانشکده پزشکی اصفهان |
spelling | doaj.art-c5bb1972fa584c28808a5556e3aa23542023-09-02T14:42:57ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2012-03-0129172888Obesity and AngiogenesisZoya Tahergurabi0Majid Khazaei1PhD Student, Student Research Committee, Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranAssociate Professor, Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranNowadays, high prevalence of obesity and its consequences is considered as a major health complication worldwide. Overweight increases risk of diseases such as hypertension, cardiovascular diseases, type 2 diabetes, certain types of cancer, gallstone, and osteoarthritis. Obesity is defined as growth of visceral white adipose tissue. On the other hand, in order to supply for metabolic needs of adipose tissue, depends on appropriate growth of blood vessels, either in number and/or in size (angiogenesis/arteriogenesis). Moreover, the very close interconnection between adipogenesis and angiogenesis has been considered in recent years. Therapeutic interventions for treating obesity by targeting vessels of adipose tissue illustrate a promising future. In this review, we discussed adipose tissue, important roles and functions of vessels in adipose tissue, obesity, and angiogenesis. We finally presented suggestions on how to use anti-angiogenesis agents for treatment of obesity as a novel approach.http://jims.mui.ac.ir/index.php/jims/article/view/1663ObesityAngiogenesisAdipogenesis |
spellingShingle | Zoya Tahergurabi Majid Khazaei Obesity and Angiogenesis مجله دانشکده پزشکی اصفهان Obesity Angiogenesis Adipogenesis |
title | Obesity and Angiogenesis |
title_full | Obesity and Angiogenesis |
title_fullStr | Obesity and Angiogenesis |
title_full_unstemmed | Obesity and Angiogenesis |
title_short | Obesity and Angiogenesis |
title_sort | obesity and angiogenesis |
topic | Obesity Angiogenesis Adipogenesis |
url | http://jims.mui.ac.ir/index.php/jims/article/view/1663 |
work_keys_str_mv | AT zoyatahergurabi obesityandangiogenesis AT majidkhazaei obesityandangiogenesis |