Liver Disease Among Mexican Americans Aged 67 Years and Older

Background: The Center for Disease Control and Prevention (CDC) reports that liver disease is a significant cause of morbidity and mortality in the US, afflicting 4.5 million people in 2018, or approximately 1.7% of the American adult population. Objective: To determine the prevalence and risk facto...

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Main Authors: Ronan P. Allencherril, Kyriakos S. Markides, Soham Al Snih
Format: Article
Language:English
Published: SAGE Publishing 2022-08-01
Series:Journal of Primary Care & Community Health
Online Access:https://doi.org/10.1177/21501319221116231
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author Ronan P. Allencherril
Kyriakos S. Markides
Soham Al Snih
author_facet Ronan P. Allencherril
Kyriakos S. Markides
Soham Al Snih
author_sort Ronan P. Allencherril
collection DOAJ
description Background: The Center for Disease Control and Prevention (CDC) reports that liver disease is a significant cause of morbidity and mortality in the US, afflicting 4.5 million people in 2018, or approximately 1.7% of the American adult population. Objective: To determine the prevalence and risk factors associated with liver disease among older Mexican Americans over 18 years of follow-up. Methods: Non-institutionalized Mexican Americans aged ≥67 years (N = 1938) from the Hispanic Established Population for the Epidemiologic Study of the Elderly (1995/96-2012/13) were studied. Measures included socio-demographic variables, self-reported liver disease, language of interview, medical conditions, hand-grip strength, physical and cognitive function, depressive symptoms, and body mass index. Generalized estimating equation models were used to estimate the odds ratio and 95% confidence interval (CI) of liver disease over time. Results: The mean age at baseline was 74.9 ± 6.0 years and 58.4% were female. The prevalence of liver disease ranged from 2.4% to 8.4%. Over time, the odds ratio of reporting liver disease was 1.17 (CI = 1.12-1.22). Older age, Spanish interview, arthritis, diabetes, heart failure, cancer, and high scores on the Mini-Mental-State-Examination were factors associated with greater odds of reporting liver disease over time. Married participants reported lower odds of liver disease over time. Conclusions: The prevalence of liver disease in this population was high, ranging from 2.4% to 8.4%. Diabetes, heart failure, arthritis, and cancer were risk factors for liver disease. Screening for liver function among patients with these morbidities may help prevent liver disease in this population with high rates of diabetes and obesity.
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spelling doaj.art-c5bb5f1b70f6420893774071822c0ce22022-12-22T04:01:41ZengSAGE PublishingJournal of Primary Care & Community Health2150-13272022-08-011310.1177/21501319221116231Liver Disease Among Mexican Americans Aged 67 Years and OlderRonan P. Allencherril0Kyriakos S. Markides1Soham Al Snih2Baylor College of Medicine, Houston, TX, USAThe University of Texas Medical Branch, Galveston, TX, USAThe University of Texas Medical Branch, Galveston, TX, USABackground: The Center for Disease Control and Prevention (CDC) reports that liver disease is a significant cause of morbidity and mortality in the US, afflicting 4.5 million people in 2018, or approximately 1.7% of the American adult population. Objective: To determine the prevalence and risk factors associated with liver disease among older Mexican Americans over 18 years of follow-up. Methods: Non-institutionalized Mexican Americans aged ≥67 years (N = 1938) from the Hispanic Established Population for the Epidemiologic Study of the Elderly (1995/96-2012/13) were studied. Measures included socio-demographic variables, self-reported liver disease, language of interview, medical conditions, hand-grip strength, physical and cognitive function, depressive symptoms, and body mass index. Generalized estimating equation models were used to estimate the odds ratio and 95% confidence interval (CI) of liver disease over time. Results: The mean age at baseline was 74.9 ± 6.0 years and 58.4% were female. The prevalence of liver disease ranged from 2.4% to 8.4%. Over time, the odds ratio of reporting liver disease was 1.17 (CI = 1.12-1.22). Older age, Spanish interview, arthritis, diabetes, heart failure, cancer, and high scores on the Mini-Mental-State-Examination were factors associated with greater odds of reporting liver disease over time. Married participants reported lower odds of liver disease over time. Conclusions: The prevalence of liver disease in this population was high, ranging from 2.4% to 8.4%. Diabetes, heart failure, arthritis, and cancer were risk factors for liver disease. Screening for liver function among patients with these morbidities may help prevent liver disease in this population with high rates of diabetes and obesity.https://doi.org/10.1177/21501319221116231
spellingShingle Ronan P. Allencherril
Kyriakos S. Markides
Soham Al Snih
Liver Disease Among Mexican Americans Aged 67 Years and Older
Journal of Primary Care & Community Health
title Liver Disease Among Mexican Americans Aged 67 Years and Older
title_full Liver Disease Among Mexican Americans Aged 67 Years and Older
title_fullStr Liver Disease Among Mexican Americans Aged 67 Years and Older
title_full_unstemmed Liver Disease Among Mexican Americans Aged 67 Years and Older
title_short Liver Disease Among Mexican Americans Aged 67 Years and Older
title_sort liver disease among mexican americans aged 67 years and older
url https://doi.org/10.1177/21501319221116231
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