Berry Phenolic Antioxidants – Implications for Human Health?
Antioxidants present in the diet may have a significant effect on the prophylaxis and progression of various diseases associated with oxidative stress. Berries contain a range of chemical compounds with antioxidant properties, including phenolic compounds. The aim of this review article is to provid...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-03-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fphar.2018.00078/full |
| _version_ | 1818541107284279296 |
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| author | Beata Olas |
| author_facet | Beata Olas |
| author_sort | Beata Olas |
| collection | DOAJ |
| description | Antioxidants present in the diet may have a significant effect on the prophylaxis and progression of various diseases associated with oxidative stress. Berries contain a range of chemical compounds with antioxidant properties, including phenolic compounds. The aim of this review article is to provide an overview of the current knowledge of such phenolic antioxidants, and to discuss whether these compounds may always be natural gifts for human health, based on both in vitro and in vivo studies. It describes the antioxidant properties of fresh berries (including aronia berries, grapes, blueberries, sea buckthorn berries, strawberries and other berries) and their various products, especially juices and wines. Some papers report that these phenolic compounds may sometimes behave like prooxidants, and sometimes demonstrate both antioxidant and prooxidant activity, while others note they do not behave the same way in vitro and in vivo. However, no unwanted or toxic effects (i.e., chemical, hematological or urinary effect) have been associated with the consumption of berries or berry juices or other extracts, especially aronia berries and aronia products in vivo, and in vitro, which may suggest that the phenolic antioxidants found in berries are natural gifts for human health. However, the phenolic compound content of berries and berry products is not always well described, and further studies are required to determine the therapeutic doses of different berry products for use in future clinical studies. Moreover, further experiments are needed to understand the beneficial effects reported so far from the mechanistic point of view. Therefore, greater attention should be paid to the development of well-controlled and high-quality clinical studies in this area. |
| first_indexed | 2024-12-11T22:04:14Z |
| format | Article |
| id | doaj.art-c5c2b2635a794216a1d9e47c613494f6 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-12-11T22:04:14Z |
| publishDate | 2018-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-c5c2b2635a794216a1d9e47c613494f62022-12-22T00:49:00ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122018-03-01910.3389/fphar.2018.00078320038Berry Phenolic Antioxidants – Implications for Human Health?Beata OlasAntioxidants present in the diet may have a significant effect on the prophylaxis and progression of various diseases associated with oxidative stress. Berries contain a range of chemical compounds with antioxidant properties, including phenolic compounds. The aim of this review article is to provide an overview of the current knowledge of such phenolic antioxidants, and to discuss whether these compounds may always be natural gifts for human health, based on both in vitro and in vivo studies. It describes the antioxidant properties of fresh berries (including aronia berries, grapes, blueberries, sea buckthorn berries, strawberries and other berries) and their various products, especially juices and wines. Some papers report that these phenolic compounds may sometimes behave like prooxidants, and sometimes demonstrate both antioxidant and prooxidant activity, while others note they do not behave the same way in vitro and in vivo. However, no unwanted or toxic effects (i.e., chemical, hematological or urinary effect) have been associated with the consumption of berries or berry juices or other extracts, especially aronia berries and aronia products in vivo, and in vitro, which may suggest that the phenolic antioxidants found in berries are natural gifts for human health. However, the phenolic compound content of berries and berry products is not always well described, and further studies are required to determine the therapeutic doses of different berry products for use in future clinical studies. Moreover, further experiments are needed to understand the beneficial effects reported so far from the mechanistic point of view. Therefore, greater attention should be paid to the development of well-controlled and high-quality clinical studies in this area.http://journal.frontiersin.org/article/10.3389/fphar.2018.00078/fullberriesphenolic compoundsantioxidantshealthoxidative stress |
| spellingShingle | Beata Olas Berry Phenolic Antioxidants – Implications for Human Health? Frontiers in Pharmacology berries phenolic compounds antioxidants health oxidative stress |
| title | Berry Phenolic Antioxidants – Implications for Human Health? |
| title_full | Berry Phenolic Antioxidants – Implications for Human Health? |
| title_fullStr | Berry Phenolic Antioxidants – Implications for Human Health? |
| title_full_unstemmed | Berry Phenolic Antioxidants – Implications for Human Health? |
| title_short | Berry Phenolic Antioxidants – Implications for Human Health? |
| title_sort | berry phenolic antioxidants implications for human health |
| topic | berries phenolic compounds antioxidants health oxidative stress |
| url | http://journal.frontiersin.org/article/10.3389/fphar.2018.00078/full |
| work_keys_str_mv | AT beataolas berryphenolicantioxidantsimplicationsforhumanhealth |