Maturation of pluripotent stem cell-derived cardiomyocytes: limitations and challenges from metabolic aspects

Maturation of pluripotent stem cell-derived cardiomyocytes: limitations and challenges from metabolic aspects

Abstract Acute coronary syndromes, such as myocardial infarction (MI), lack effective therapies beyond heart transplantation, which is often hindered by donor scarcity and postoperative complications. Human induced pluripotent stem cells (hiPSCs) offer the possibility of myocardial regeneration by d...

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Podrobná bibliografie
Hlavní autoři: Xi Jiang, Xin Lian, Kun Wei, Jie Zhang, Kaihua Yu, Haoming Li, Haichun Ma, Yin Cai, Lei Pang
Médium: Článek
Jazyk:English
Vydáno: BMC 2024-10-01
Edice:Stem Cell Research & Therapy
Témata:
Acute coronary syndromes
Myocardial infarction
Induced pluripotent stem cells
iPSC-cardiomyocytes
Maturation
Energy metabolism
On-line přístup:https://doi.org/10.1186/s13287-024-03961-4

Internet

https://doi.org/10.1186/s13287-024-03961-4

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