Maturation of pluripotent stem cell-derived cardiomyocytes: limitations and challenges from metabolic aspects

Maturation of pluripotent stem cell-derived cardiomyocytes: limitations and challenges from metabolic aspects

Abstract Acute coronary syndromes, such as myocardial infarction (MI), lack effective therapies beyond heart transplantation, which is often hindered by donor scarcity and postoperative complications. Human induced pluripotent stem cells (hiPSCs) offer the possibility of myocardial regeneration by d...

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Detalhes bibliográficos
Principais autores:	Xi Jiang, Xin Lian, Kun Wei, Jie Zhang, Kaihua Yu, Haoming Li, Haichun Ma, Yin Cai, Lei Pang
Formato:	Artigo
Idioma:	English
Publicado em:	BMC 2024-10-01
coleção:	Stem Cell Research & Therapy
Assuntos:	Acute coronary syndromes Myocardial infarction Induced pluripotent stem cells iPSC-cardiomyocytes Maturation Energy metabolism
Acesso em linha:	https://doi.org/10.1186/s13287-024-03961-4

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