Maturation of pluripotent stem cell-derived cardiomyocytes: limitations and challenges from metabolic aspects

Maturation of pluripotent stem cell-derived cardiomyocytes: limitations and challenges from metabolic aspects

Abstract Acute coronary syndromes, such as myocardial infarction (MI), lack effective therapies beyond heart transplantation, which is often hindered by donor scarcity and postoperative complications. Human induced pluripotent stem cells (hiPSCs) offer the possibility of myocardial regeneration by d...

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Bibliographic Details
Main Authors: Xi Jiang, Xin Lian, Kun Wei, Jie Zhang, Kaihua Yu, Haoming Li, Haichun Ma, Yin Cai, Lei Pang
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Stem Cell Research & Therapy
Subjects:
Acute coronary syndromes
Myocardial infarction
Induced pluripotent stem cells
iPSC-cardiomyocytes
Maturation
Energy metabolism
Online Access:https://doi.org/10.1186/s13287-024-03961-4

Internet

https://doi.org/10.1186/s13287-024-03961-4

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