Targeting of activated fibroblasts for imaging and therapy

Targeting of activated fibroblasts for imaging and therapy

Abstract Tumors form a complex environment consisting of a variety of non-malignant cells. Especially cancer-associated fibroblasts have been shown to have an important role for different aspects of malignant tumors such as migration, metastasis, resistance to chemotherapy and immunosuppression. The...

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Bibliographic Details
Main Authors: Thomas Lindner, Anastasia Loktev, Frederik Giesel, Clemens Kratochwil, Annette Altmann, Uwe Haberkorn
Format: Article
Language:English
Published: SpringerOpen 2019-07-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Cancer-associated fibroblast
Tumor stroma
Fibroblast activation protein
Inhibitors
Imaging
Online Access:http://link.springer.com/article/10.1186/s41181-019-0069-0

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