Effects of continuous moderate exercise with partial blood flow restriction during hemodialysis: A protocol for a randomized clinical trial
Chronic kidney disease (CKD) is associated with physical weakness and increased oxidative stress and inflammation levels. Rehabilitation programs are associated with an improvement in the functional capacity, inflammatory and oxidative stress profile. Exercise associated with blood flow restriction...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-01-01
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| Series: | MethodsX |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2215016119300068 |
| _version_ | 1818135796210728960 |
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| author | Rodrigo Kohn Cardoso Aline Machado Araujo Rafael Bueno Orcy Maristela Bohlke Jean Pierre Oses Fabrício Boscolo Del Vecchio Franklin Correa Barcellos Maria Cristina Gonzalez Airton José Rombaldi |
| author_facet | Rodrigo Kohn Cardoso Aline Machado Araujo Rafael Bueno Orcy Maristela Bohlke Jean Pierre Oses Fabrício Boscolo Del Vecchio Franklin Correa Barcellos Maria Cristina Gonzalez Airton José Rombaldi |
| author_sort | Rodrigo Kohn Cardoso |
| collection | DOAJ |
| description | Chronic kidney disease (CKD) is associated with physical weakness and increased oxidative stress and inflammation levels. Rehabilitation programs are associated with an improvement in the functional capacity, inflammatory and oxidative stress profile. Exercise associated with blood flow restriction (BFR) has been demonstrating positive effects in training programs, but there is lack information about exercise with BFR in CKD. Therefore, the aim of the present study is to describe a protocol using continuous moderate exercise with blood flow restriction (BFR) applied during hemodialysis (HD) to measures health indicators and immune system and oxidative stress parameters in CKD patients. Methods: A RTC will be conducted with 42 patients in HD. Baseline measures will be compared with final measures (anthropometric, cardiorespiratory, biochemical, muscle fitness, nutritional and behavioral questions). Participants will be randomly allocated to: 1) Continuous moderate exercise group with BFR; 2) Continuous moderate exercise group without BFR; 3) Control group without exercise. The intervention will be 12 weeks long during HD session. Patients will perform 20 min of continuous moderate exercise on a stationary bicycle three times a week. The present study is expected to generate significant information about the role of exercise with BFR in patients with CKD during HD. Keywords: Chronic kidney failure, Hemodialysis, Rehabilitation, Training, Inflammation, Oxidative stress, Quality of life |
| first_indexed | 2024-12-11T09:30:12Z |
| format | Article |
| id | doaj.art-c5c5bc2702a442b0bd443ce566d69c2d |
| institution | Directory Open Access Journal |
| issn | 2215-0161 |
| language | English |
| last_indexed | 2024-12-11T09:30:12Z |
| publishDate | 2019-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | MethodsX |
| spelling | doaj.art-c5c5bc2702a442b0bd443ce566d69c2d2022-12-22T01:13:03ZengElsevierMethodsX2215-01612019-01-016190198Effects of continuous moderate exercise with partial blood flow restriction during hemodialysis: A protocol for a randomized clinical trialRodrigo Kohn Cardoso0Aline Machado Araujo1Rafael Bueno Orcy2Maristela Bohlke3Jean Pierre Oses4Fabrício Boscolo Del Vecchio5Franklin Correa Barcellos6Maria Cristina Gonzalez7Airton José Rombaldi8Post-Graduate Program of Physical Education, Federal University of Pelotas, Pelotas, RS, BrazilPost-Graduate Program of Physical Education, Federal University of Pelotas, Pelotas, RS, BrazilDepartment of Physiology and Pharmacology, Federal University of Pelotas, Pelotas, RS, Brazil; Corresponding author.Dialysis and Renal Transplantation Unit, São Francisco de Paula University Hospital, Catholic University of Pelotas, Pelotas, RS, Brazil; Post-Graduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas, RS, BrazilPost-Graduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas, RS, BrazilPost-Graduate Program of Physical Education, Federal University of Pelotas, Pelotas, RS, BrazilDialysis and Renal Transplantation Unit, São Francisco de Paula University Hospital, Catholic University of Pelotas, Pelotas, RS, BrazilPost-Graduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas, RS, BrazilPost-Graduate Program of Physical Education, Federal University of Pelotas, Pelotas, RS, BrazilChronic kidney disease (CKD) is associated with physical weakness and increased oxidative stress and inflammation levels. Rehabilitation programs are associated with an improvement in the functional capacity, inflammatory and oxidative stress profile. Exercise associated with blood flow restriction (BFR) has been demonstrating positive effects in training programs, but there is lack information about exercise with BFR in CKD. Therefore, the aim of the present study is to describe a protocol using continuous moderate exercise with blood flow restriction (BFR) applied during hemodialysis (HD) to measures health indicators and immune system and oxidative stress parameters in CKD patients. Methods: A RTC will be conducted with 42 patients in HD. Baseline measures will be compared with final measures (anthropometric, cardiorespiratory, biochemical, muscle fitness, nutritional and behavioral questions). Participants will be randomly allocated to: 1) Continuous moderate exercise group with BFR; 2) Continuous moderate exercise group without BFR; 3) Control group without exercise. The intervention will be 12 weeks long during HD session. Patients will perform 20 min of continuous moderate exercise on a stationary bicycle three times a week. The present study is expected to generate significant information about the role of exercise with BFR in patients with CKD during HD. Keywords: Chronic kidney failure, Hemodialysis, Rehabilitation, Training, Inflammation, Oxidative stress, Quality of lifehttp://www.sciencedirect.com/science/article/pii/S2215016119300068 |
| spellingShingle | Rodrigo Kohn Cardoso Aline Machado Araujo Rafael Bueno Orcy Maristela Bohlke Jean Pierre Oses Fabrício Boscolo Del Vecchio Franklin Correa Barcellos Maria Cristina Gonzalez Airton José Rombaldi Effects of continuous moderate exercise with partial blood flow restriction during hemodialysis: A protocol for a randomized clinical trial MethodsX |
| title | Effects of continuous moderate exercise with partial blood flow restriction during hemodialysis: A protocol for a randomized clinical trial |
| title_full | Effects of continuous moderate exercise with partial blood flow restriction during hemodialysis: A protocol for a randomized clinical trial |
| title_fullStr | Effects of continuous moderate exercise with partial blood flow restriction during hemodialysis: A protocol for a randomized clinical trial |
| title_full_unstemmed | Effects of continuous moderate exercise with partial blood flow restriction during hemodialysis: A protocol for a randomized clinical trial |
| title_short | Effects of continuous moderate exercise with partial blood flow restriction during hemodialysis: A protocol for a randomized clinical trial |
| title_sort | effects of continuous moderate exercise with partial blood flow restriction during hemodialysis a protocol for a randomized clinical trial |
| url | http://www.sciencedirect.com/science/article/pii/S2215016119300068 |
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