Cervicocranialgia: rationale for and evaluation of the clinical efficiency of therapy with the Russian generics of dexketoprofen and tolperisone
Objective: to comparatively evaluate the clinical efficiency of cervicocranialgia therapy with dexketoprofen (flamadex) and tolperisone (calmyrex), as well as with their combination. Patients and methods. The investigation enrolled 90 patients aged 30–60 years with cervicocranialgia, who were random...
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2019-12-01
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| Series: | Неврология, нейропсихиатрия, психосоматика |
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| Online Access: | https://nnp.ima-press.net/nnp/article/view/1216 |
| _version_ | 1797876387460153344 |
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| author | M. N. Dadasheva G. I. Nurullina R. V. Gorenkov |
| author_facet | M. N. Dadasheva G. I. Nurullina R. V. Gorenkov |
| author_sort | M. N. Dadasheva |
| collection | DOAJ |
| description | Objective: to comparatively evaluate the clinical efficiency of cervicocranialgia therapy with dexketoprofen (flamadex) and tolperisone (calmyrex), as well as with their combination. Patients and methods. The investigation enrolled 90 patients aged 30–60 years with cervicocranialgia, who were randomized into three equal groups. Group 1 included 7 men and 23 women who took dexketoprofen; Group 2 consisted of 13 men and 17 women who were prescribed dexketoprofen and tolperisone; Group 3 comprised 18 men and 12 women who used tolperisone. The three patient groups underwent assessment of the intensity of pain on a visual analogue scale and the degree of muscle tone on a 3-point scale and evaluation of the efficiency of therapy and the hemodynamic effect of the drugs in the common carotid and vertebral arteries. Results and discussion. In all the groups, their treatment reversed neck pain, headache, and dizziness, normalized muscle tone, and improved hemodynamics in the carotid and vertebral arteries. The effect was more pronounced in patients receiving combination treatment (Group 2). The therapy showed a high safety and a good tolerability. Conclusion. Dexketoprofen and tolperisone have been demonstrated to be effective and safe in treating cervicocranialgia. |
| first_indexed | 2024-04-10T02:02:26Z |
| format | Article |
| id | doaj.art-c5c606f6b29047f59f30d66ebb1877ef |
| institution | Directory Open Access Journal |
| issn | 2074-2711 2310-1342 |
| language | Russian |
| last_indexed | 2024-04-10T02:02:26Z |
| publishDate | 2019-12-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Неврология, нейропсихиатрия, психосоматика |
| spelling | doaj.art-c5c606f6b29047f59f30d66ebb1877ef2023-03-13T08:42:19ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422019-12-01114949910.14412/2074-2711-2019-4-94-99928Cervicocranialgia: rationale for and evaluation of the clinical efficiency of therapy with the Russian generics of dexketoprofen and tolperisoneM. N. Dadasheva0G. I. Nurullina1R. V. Gorenkov2M.F. Vladimirsky Moscow Regional Research Clinical InstituteKazan State Medical University, Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaObjective: to comparatively evaluate the clinical efficiency of cervicocranialgia therapy with dexketoprofen (flamadex) and tolperisone (calmyrex), as well as with their combination. Patients and methods. The investigation enrolled 90 patients aged 30–60 years with cervicocranialgia, who were randomized into three equal groups. Group 1 included 7 men and 23 women who took dexketoprofen; Group 2 consisted of 13 men and 17 women who were prescribed dexketoprofen and tolperisone; Group 3 comprised 18 men and 12 women who used tolperisone. The three patient groups underwent assessment of the intensity of pain on a visual analogue scale and the degree of muscle tone on a 3-point scale and evaluation of the efficiency of therapy and the hemodynamic effect of the drugs in the common carotid and vertebral arteries. Results and discussion. In all the groups, their treatment reversed neck pain, headache, and dizziness, normalized muscle tone, and improved hemodynamics in the carotid and vertebral arteries. The effect was more pronounced in patients receiving combination treatment (Group 2). The therapy showed a high safety and a good tolerability. Conclusion. Dexketoprofen and tolperisone have been demonstrated to be effective and safe in treating cervicocranialgia.https://nnp.ima-press.net/nnp/article/view/1216cervicocranialgianeck painheadachedizzinessdexketoprofen (flamadex)tolperisone (calmyrex) |
| spellingShingle | M. N. Dadasheva G. I. Nurullina R. V. Gorenkov Cervicocranialgia: rationale for and evaluation of the clinical efficiency of therapy with the Russian generics of dexketoprofen and tolperisone Неврология, нейропсихиатрия, психосоматика cervicocranialgia neck pain headache dizziness dexketoprofen (flamadex) tolperisone (calmyrex) |
| title | Cervicocranialgia: rationale for and evaluation of the clinical efficiency of therapy with the Russian generics of dexketoprofen and tolperisone |
| title_full | Cervicocranialgia: rationale for and evaluation of the clinical efficiency of therapy with the Russian generics of dexketoprofen and tolperisone |
| title_fullStr | Cervicocranialgia: rationale for and evaluation of the clinical efficiency of therapy with the Russian generics of dexketoprofen and tolperisone |
| title_full_unstemmed | Cervicocranialgia: rationale for and evaluation of the clinical efficiency of therapy with the Russian generics of dexketoprofen and tolperisone |
| title_short | Cervicocranialgia: rationale for and evaluation of the clinical efficiency of therapy with the Russian generics of dexketoprofen and tolperisone |
| title_sort | cervicocranialgia rationale for and evaluation of the clinical efficiency of therapy with the russian generics of dexketoprofen and tolperisone |
| topic | cervicocranialgia neck pain headache dizziness dexketoprofen (flamadex) tolperisone (calmyrex) |
| url | https://nnp.ima-press.net/nnp/article/view/1216 |
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