Design, synthesis and anticancer evaluation of various aryl amide derivatives of thiazole-benzothiazole-pyrimidines

Design, synthesis and anticancer evaluation of various aryl amide derivatives of thiazole-benzothiazole-pyrimidines

We have developed a new series of various aryl amide derivatives of thiazole-benzothaizole-pyrimidines (13a-j). Their chemical structures were characterized by 1HNMR, 13CNMR and mass spectral data. Further, in vitro anticancer properties of newly developed compounds 13a-j were investigated against f...

Full description

Bibliographic Details
Main Authors:	Shanti Priya Vemuluri, Vijaya Laxmi Somarapu, Laxminarayana Eppakayala
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Series:	Results in Chemistry
Subjects:	NSC-710305 Benzothiazole Imatinib Pyrimidine and anticancer activity
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211715624000997

Similar Items

Design, synthesis and biological evaluation of aryl urea derivatives of oxazole-pyrimidine as anticancer agents
by: Veeranjaneyulu Pattabi, et al.
Published: (2024-01-01)

Copper-Coordinated Thiazoles and Benzothiazoles: A Perfect Alliance in the Search for Compounds with Antibacterial and Antifungal Activity
by: Raúl Colorado-Peralta, et al.
Published: (2023-04-01)

Benzothiazole and Chromone Derivatives as Potential ATR Kinase Inhibitors and Anticancer Agents
by: Mykhaylo Frasinyuk, et al.
Published: (2022-07-01)

Synthesis and Antimicrobial, Anticancer and Anti-Oxidant Activities of Novel 2,3-Dihydropyrido[2,3-d]pyrimidine-4-one and Pyrrolo[2,1-b][1,3]benzothiazole Derivatives via Microwave-Assisted Synthesis
by: Aamal A. Al-Mutairi, et al.
Published: (2022-02-01)

Design, synthesis and anticancer evaluation of aryl pyrimidine-thiadiazoles
by: Veera Reddy Yenireddy, et al.
Published: (2024-01-01)

Synthesis and biological evaluation of novel benzothiazole derivatives as potential anticancer and antiinflammatory agents
by: Xuemei Xu, et al.
Published: (2024-03-01)

Inhibition Properties of Some Pyrimidine Derivatives as Anticancer Agents on Glutathione S-Transferase
by: Hatice Esra Duran
Published: (2021-10-01)

Synthetic Approaches to Biologically Active C-2-Substituted Benzothiazoles
by: Bagrat A. Shainyan, et al.
Published: (2022-04-01)

Research Progress of Benzothiazole and Benzoxazole Derivatives in the Discovery of Agricultural Chemicals
by: Yue Zou, et al.
Published: (2023-06-01)

Efficient and Eco-Friendly Perspectives for C-H Arylation of Benzothiazole Utilizing Pd Nanoparticle-Decorated Chitosan
by: Mohamed Mokhtar M. Mostafa, et al.
Published: (2022-09-01)

Discovery of pyrimidine-tethered benzothiazole derivatives as novel anti-tubercular agents towards multi- and extensively drug resistant Mycobacterium tuberculosis
by: Loah R. Hemeda, et al.
Published: (2023-12-01)

Synthesis and Preliminary Antibacterial Study of New 2-Mercapto-1, 3- Benzothiazole DerivativesWith Expected Biological Activity
by: Samer Abbas Ali
Published: (2013-06-01)

In vitro antimitotic activity and in silico study of some 6-fluoro-triazolo-benzothiazole analogues
by: Naresh Podila, et al.
Published: (2023-09-01)

Synthesis, Characterization, and Anticancer Activity of Benzothiazole Aniline Derivatives and Their Platinum (II) Complexes as New Chemotherapy Agents
by: Md. Kamrul Islam, et al.
Published: (2021-08-01)

Crystal structure of 3-(benzo[d]thiazol-2-yl)-6-methyl-2H-chromen-2-one
by: Amira E. M. Abdallah, et al.
Published: (2023-05-01)

Unsymmetrical Pd(II) Pincer Complexes with Benzothiazole and Thiocarbamate Flanking Units: Expedient Solvent-Free Synthesis and Anticancer Potential
by: Vladimir A. Kozlov, et al.
Published: (2023-12-01)

The Microwave Rotational Electric Resonance (RER) Spectrum of Benzothiazole
by: Hamza El Hadki, et al.
Published: (2023-04-01)

Benzothiazole-Containing Analogues of Triclocarban with Potent Antibacterial Activity
by: Alessia Catalano, et al.
Published: (2021-07-01)

Eelectrosynthesis of benzothiazole derivatives via C–H thiolation
by: Ahdenov Reza, et al.
Published: (2022-05-01)

Pioneering Synthetic Strategies of 2-Substituted Benzothiazoles Using 2-Aminothiophenol
by: Sunita Teli, et al.
Published: (2024-01-01)

Experimental and In Silico Evaluation of New Heteroaryl Benzothiazole Derivatives as Antimicrobial Agents
by: Alexander Zubenko, et al.
Published: (2022-11-01)

Recent advances and SAR study of 2-substituted benzothiazole scaffold based potent chemotherapeutic agents
by: Kashif Haider, et al.
Published: (2022-01-01)

Benzothiazole-Phthalimide Hybrids as Anti-Breast Cancer and Antimicrobial Agents
by: Alexia Barbarossa, et al.
Published: (2023-11-01)

Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry
by: Xiang Gao, et al.
Published: (2020-04-01)

Evaluation of The Antibacterial Effects of The New Benzothiazole and Tetrahydropyrimidine Derivatives against Streptococcus Iniae, Edwardsiella Tarda and Aeromonas Hydrophila as Some Zoonotic Bacterial Pathogens
by: Reza Aryan, et al.
Published: (2016-08-01)

Screening and Molecular Docking of Novel Benzothiazole Derivatives as Potential Antimicrobial Agents
by: Mohamed A. Morsy, et al.
Published: (2020-04-01)

Pyrimidine and Pyrrolidine Compounds /
by: Hendrix, Tabatha, author 648455, et al.
Published: (2012)

Modern Approaches to the Synthesis and Transformations of Practically Valuable Benzothiazole Derivatives
by: Larisa V. Zhilitskaya, et al.
Published: (2021-04-01)

One-Pot Synthesis of Benzoxazole/Benzothiazole-Substituted Esters by Michael Addition: A Selective Construction of C-N/C-S Bonds
by: Zhi-Ying Gong, et al.
Published: (2023-03-01)

Crystal structure of 2-{[5-(methylsulfanyl)-4-phenyl-4H-1,2,4-triazol-3-yl]methyl}benzo[d]thiazole
by: Rasha A. Azzam, et al.
Published: (2023-09-01)

Synthesis of a benzothiazole-based structure as a selective colorimetric-fluorogenic cyanate chemosensor
by: Kayhan Emine, et al.
Published: (2023-12-01)

DBUHI3 complex an efficient catalyst for the synthesis of 2-phenyl benzimidazole and benzothiazole derivatives
by: Gawade Ramesh, et al.
Published: (2023-01-01)

Synthesis of Homodrimane Sesquiterpenoids Bearing 1,3-Benzothiazole Unit and Their Antimicrobial Activity Evaluation
by: Lidia Lungu, et al.
Published: (2022-08-01)

In Silico and In Vitro Studies of Benzothiazole-Isothioureas Derivatives as a Multitarget Compound for Alzheimer’s Disease
by: Martha Cecilia Rosales Hernández, et al.
Published: (2022-10-01)

Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors
by: Jaka Dernovšek, et al.
Published: (2021-08-01)

A Near-infrared Benzothiazole-based Chemodosimeter for Rapid and Selective Detection of Hydrogen Sulfide
by: Safacan KOLEMEN
Published: (2021-05-01)

Design, Synthesis and Evaluation of New Multifunctional Benzothiazoles as Photoprotective, Antioxidant and Antiproliferative Agents
by: Riccardo Barbari, et al.
Published: (2022-12-01)

Facile protocol, metal-free, one-pot synthesis of 2-amino-4H-chromenes, benzimidazoles, and benzothiazoles via acidic ionic liquids based on pyridinium
by: Fereshteh Norouzi, et al.
Published: (2024-01-01)

In Silico Prediction of Binding Affinities of Hybrid Molecules of Benzothiazole cross-linked with Hydroxamic acid by certain linkers
by: yazen alqaysi, et al.
Published: (2024-01-01)

Synthesis, Physicochemical Properties and Molecular Docking of New Benzothiazole Derivatives as Antimicrobial Agents Targeting DHPS Enzyme
by: Rasha A. Azzam, et al.
Published: (2022-12-01)