Combined evaluation of both WEE1 and phosphorylated cyclin dependent kinase 1 expressions in oral squamous cell carcinomas predicts cancer recurrence and progression

Combined evaluation of both WEE1 and phosphorylated cyclin dependent kinase 1 expressions in oral squamous cell carcinomas predicts cancer recurrence and progression

Background/purpose: WEE1 is a mitotic inhibitor at G2 checkpoint of the cell cycle that negatively regulates cyclin-dependent kinase 1 (CDK1) through inhibitory phosphorylation. This study assessed whether the expressions of both WEE1 and phosphorylated CDK1 in specimens of oral squamous cell carcin...

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Bibliographic Details
Main Authors:	Yu-Hsueh Wu, Julia Yu-Fong Chang, Chun-Pin Chiang, Yi-Ping Wang
Format:	Article
Language:	English
Published:	Elsevier 2022-10-01
Series:	Journal of Dental Sciences
Subjects:	WEE1 Cyclin-dependent kinase 1 Oral squamous cell carcinoma Cell cycle checkpoint Immunohisto-chemistry
Online Access:	http://www.sciencedirect.com/science/article/pii/S1991790222001921

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