The role of Pharmacist in optimizing antibiotic therapy. Impact of pharmaceutical consultations on antibiotic and antimicrobial drugs consumption
Introduction According to the data provided by the National Antibiotic Protection Program, approximately 50% of antibiotic prescriptions are inappropriate and every tenth hospitalized patient receives antibiotics for unjustified reasons. Overuse of this group of drugs has led to antibiotic resistanc...
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| Format: | Article |
| Language: | Polish |
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Polish Pharmaceutical Society
2023-12-01
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| Series: | Farmacja Polska |
| Subjects: | |
| Online Access: | https://www.ptfarm.pl/download/?file=File%2FFarmacja+Polska%2F2023%2F9%2F04_SZ_Rola_farmaceuty_w_optymalizacji_antybiot.pdf |
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| author | Daniel Orzechowski Adrian Bryła Krystyna Chmal-Jagiełło |
| author_facet | Daniel Orzechowski Adrian Bryła Krystyna Chmal-Jagiełło |
| author_sort | Daniel Orzechowski |
| collection | DOAJ |
| description | Introduction
According to the data provided by the National Antibiotic Protection Program, approximately 50% of antibiotic prescriptions are inappropriate and every tenth hospitalized patient receives antibiotics for unjustified reasons. Overuse of this group of drugs has led to antibiotic resistance, which- according to the European Center for Disease Prevention and Control (ECDC) is a significant clinical problem in Poland. Extended hospitalization time due to infection and costs associated with antibiotic therapy are becoming an important financial problem. The report of the Supreme Audit Office (NIK) estimated them in 2019 at 800 million PLN during one year.
Aim
The aim of the study was to assess the impact of the introduced pharmaceutical consultations and other elements of antibiotic stewardship on the use of antimicrobial drugs in the Ludwik Rydygier Memorial Specialized Hospital in Krakow.
Methods
Prescribed second – and thitrd – line drugs vere verified by a pharmacist from The Antibiotics Team during dispensing drugs from The Hospital Pharmacy. After verifying the of antibiotic therapy, the pharmacist approved the dispense of the drug or performed consultations.
Results
The effect of the efforts carried out by the antibiotic stewardship team is a 35% decrease in the frequency of 2nd and 3rd line anti-microbial drugs dispensed within 2 years. The decrease in the use of carbapenems was 51% and the use of intravenous fluoroquinolones was reduced by 79%.
Conclusions
The prospective pharmacist control at The Ludwik Rydygier Memorial Specialized Hospital in Krakow, antibiotic therapy was associated with changes in the structure and quantity of antimicrobial drugs dispensed. It is not clear what type of pharmacist activity (empiric ntibiotics therapy consultations, de-escalation, drug concentration-monitored therapy consultations) contributed the most to reducing the number of drugs dispensed. This issue requires further research and is particularly important in connection with the implementation of clinical pharmacy services in Poland, their evaluation and standardization. |
| first_indexed | 2024-03-08T18:56:12Z |
| format | Article |
| id | doaj.art-c5cb10352f6341598caec43bb410e85c |
| institution | Directory Open Access Journal |
| issn | 0014-8261 |
| language | Polish |
| last_indexed | 2024-03-08T18:56:12Z |
| publishDate | 2023-12-01 |
| publisher | Polish Pharmaceutical Society |
| record_format | Article |
| series | Farmacja Polska |
| spelling | doaj.art-c5cb10352f6341598caec43bb410e85c2023-12-28T13:32:11ZpolPolish Pharmaceutical SocietyFarmacja Polska0014-82612023-12-0179954955610.32383/farmpol/177268177268The role of Pharmacist in optimizing antibiotic therapy. Impact of pharmaceutical consultations on antibiotic and antimicrobial drugs consumptionDaniel Orzechowski0https://orcid.org/0000-0002-4958-6909Adrian Bryła1https://orcid.org/0000-0002-6795-2052Krystyna Chmal-Jagiełło2https://orcid.org/0000-0002-3001-4230Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie sp. z o.o., PolskaSzpital Specjalistyczny im. Ludwika Rydygiera w Krakowie sp. z o.o., PolskaSzpital Specjalistyczny im. Ludwika Rydygiera w Krakowie sp. z o.o., PolskaIntroduction According to the data provided by the National Antibiotic Protection Program, approximately 50% of antibiotic prescriptions are inappropriate and every tenth hospitalized patient receives antibiotics for unjustified reasons. Overuse of this group of drugs has led to antibiotic resistance, which- according to the European Center for Disease Prevention and Control (ECDC) is a significant clinical problem in Poland. Extended hospitalization time due to infection and costs associated with antibiotic therapy are becoming an important financial problem. The report of the Supreme Audit Office (NIK) estimated them in 2019 at 800 million PLN during one year. Aim The aim of the study was to assess the impact of the introduced pharmaceutical consultations and other elements of antibiotic stewardship on the use of antimicrobial drugs in the Ludwik Rydygier Memorial Specialized Hospital in Krakow. Methods Prescribed second – and thitrd – line drugs vere verified by a pharmacist from The Antibiotics Team during dispensing drugs from The Hospital Pharmacy. After verifying the of antibiotic therapy, the pharmacist approved the dispense of the drug or performed consultations. Results The effect of the efforts carried out by the antibiotic stewardship team is a 35% decrease in the frequency of 2nd and 3rd line anti-microbial drugs dispensed within 2 years. The decrease in the use of carbapenems was 51% and the use of intravenous fluoroquinolones was reduced by 79%. Conclusions The prospective pharmacist control at The Ludwik Rydygier Memorial Specialized Hospital in Krakow, antibiotic therapy was associated with changes in the structure and quantity of antimicrobial drugs dispensed. It is not clear what type of pharmacist activity (empiric ntibiotics therapy consultations, de-escalation, drug concentration-monitored therapy consultations) contributed the most to reducing the number of drugs dispensed. This issue requires further research and is particularly important in connection with the implementation of clinical pharmacy services in Poland, their evaluation and standardization.https://www.ptfarm.pl/download/?file=File%2FFarmacja+Polska%2F2023%2F9%2F04_SZ_Rola_farmaceuty_w_optymalizacji_antybiot.pdfantibiotic therapy managementoptimization of pharmacotherapyclinical pharmacistdrug resistance of microorganismsde-escalation control |
| spellingShingle | Daniel Orzechowski Adrian Bryła Krystyna Chmal-Jagiełło The role of Pharmacist in optimizing antibiotic therapy. Impact of pharmaceutical consultations on antibiotic and antimicrobial drugs consumption Farmacja Polska antibiotic therapy management optimization of pharmacotherapy clinical pharmacist drug resistance of microorganisms de-escalation control |
| title | The role of Pharmacist in optimizing antibiotic therapy.
Impact of pharmaceutical consultations on antibiotic and antimicrobial drugs consumption |
| title_full | The role of Pharmacist in optimizing antibiotic therapy.
Impact of pharmaceutical consultations on antibiotic and antimicrobial drugs consumption |
| title_fullStr | The role of Pharmacist in optimizing antibiotic therapy.
Impact of pharmaceutical consultations on antibiotic and antimicrobial drugs consumption |
| title_full_unstemmed | The role of Pharmacist in optimizing antibiotic therapy.
Impact of pharmaceutical consultations on antibiotic and antimicrobial drugs consumption |
| title_short | The role of Pharmacist in optimizing antibiotic therapy.
Impact of pharmaceutical consultations on antibiotic and antimicrobial drugs consumption |
| title_sort | role of pharmacist in optimizing antibiotic therapy impact of pharmaceutical consultations on antibiotic and antimicrobial drugs consumption |
| topic | antibiotic therapy management optimization of pharmacotherapy clinical pharmacist drug resistance of microorganisms de-escalation control |
| url | https://www.ptfarm.pl/download/?file=File%2FFarmacja+Polska%2F2023%2F9%2F04_SZ_Rola_farmaceuty_w_optymalizacji_antybiot.pdf |
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