Feasibility and Accuracy of Transduodenal Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Solid Lesions Using a 19-Gauge Flexible Needle: A Multicenter Study
Background/Aims Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is the go-to method for obtaining samples from gastrointestinal tract and pancreatic lesions. When the transduodenal approach is utilized, the use of a more flexible needle, such as a nitinol 19-gauge (G) needle, has been...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Korean Society of Gastrointestinal Endoscopy
2021-03-01
|
| Series: | Clinical Endoscopy |
| Subjects: | |
| Online Access: | http://www.e-ce.org/upload/pdf/ce-2020-056.pdf |
| _version_ | 1827615182829912064 |
|---|---|
| author | Germana de Nucci Maria Chiara Petrone Nicola Imperatore Edoardo Forti Roberto Grassia Silvia Giovanelli Laura Ottaviani Vincenzo Mirante Giuseppe Sabatino Carlo Fabbri Mauro Manno Paolo Giorgio Arcidiacono Gianpiero Manes |
| author_facet | Germana de Nucci Maria Chiara Petrone Nicola Imperatore Edoardo Forti Roberto Grassia Silvia Giovanelli Laura Ottaviani Vincenzo Mirante Giuseppe Sabatino Carlo Fabbri Mauro Manno Paolo Giorgio Arcidiacono Gianpiero Manes |
| author_sort | Germana de Nucci |
| collection | DOAJ |
| description | Background/Aims Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is the go-to method for obtaining samples from gastrointestinal tract and pancreatic lesions. When the transduodenal approach is utilized, the use of a more flexible needle, such as a nitinol 19-gauge (G) needle, has been recommended. The aim of this study was to evaluate the feasibility and accuracy of 19-G flexible aspiration needles in obtaining samples from solid lesions through a transduodenal approach. Methods This was a retrospective analysis of prospectively collected data from eight Italian endoscopy centers. Consecutive patients with solid lesions who underwent transduodenal EUS-FNA with a 19-G flexible needle were included. Results A total of 201 patients were enrolled. According to histology, EUS, radiology and 12 months of follow-up, 151 patients had malignant lesions and 50 patients had benign lesions. EUS-FNA was feasible in all cases. An adequate histologic sample was obtained in all except eight cases (96.1%). The sensitivity of EUS-FNA was 92.1% (95% confidence interval [CI], 86.8%–95.7%), and the specificity was 100% (95% CI, 90.5%–100%). The positive predictive value was 100% (95% CI, 93.4%–100%), and the negative predictive value was 74% (95% CI, 62.8%–82.7%). The diagnostic accuracy was 93.5% (95% CI, 89.2%–96.5%). Conclusions The transduodenal approach for obtaining samples from solid lesions using a 19-G flexible needle seems feasible and accurate. |
| first_indexed | 2024-03-09T09:07:26Z |
| format | Article |
| id | doaj.art-c5d0b052567e49f3aee1d0925e5e39fa |
| institution | Directory Open Access Journal |
| issn | 2234-2400 2234-2443 |
| language | English |
| last_indexed | 2024-03-09T09:07:26Z |
| publishDate | 2021-03-01 |
| publisher | Korean Society of Gastrointestinal Endoscopy |
| record_format | Article |
| series | Clinical Endoscopy |
| spelling | doaj.art-c5d0b052567e49f3aee1d0925e5e39fa2023-12-02T10:03:50ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432021-03-0154222923510.5946/ce.2020.0567364Feasibility and Accuracy of Transduodenal Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Solid Lesions Using a 19-Gauge Flexible Needle: A Multicenter StudyGermana de Nucci0Maria Chiara Petrone1Nicola Imperatore2Edoardo Forti3Roberto Grassia4Silvia Giovanelli5Laura Ottaviani6Vincenzo Mirante7Giuseppe Sabatino8Carlo Fabbri9Mauro Manno10Paolo Giorgio Arcidiacono11Gianpiero Manes12 Gastroenterology and Endoscopy Unit, ASST Rhodense, Garbagnate Milanese, Milan, Italy Bilio Pancreatic Endoscopy and Endoscopy Ultrasound Unit, San Raffaele Hospital, Milan, Italy Gastroenterology Unit, Federico II University, Naples, Italy Endoscopy Unit, Ca Grande Niguarda Hospital, Milan, Italy Endoscopy Unit, Cremona Hospital, Cremona, Italy Gastroenterology and Endoscopy Unit, Forlì-Cesena Hospital, Forlì, Italy Gastroenterology Unit, Santa Maria Hospital, Perugia, Italy Endoscopy Unit, Carpi Civil Hospital, Carpi, Italy Gastroenterology Unit, Cosenza Civil Hospital, Cosenza, Italy Gastroenterology and Endoscopy Unit, Forlì-Cesena Hospital, Forlì, Italy Endoscopy Unit, Carpi Civil Hospital, Carpi, Italy Bilio Pancreatic Endoscopy and Endoscopy Ultrasound Unit, San Raffaele Hospital, Milan, Italy Gastroenterology and Endoscopy Unit, ASST Rhodense, Garbagnate Milanese, Milan, ItalyBackground/Aims Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is the go-to method for obtaining samples from gastrointestinal tract and pancreatic lesions. When the transduodenal approach is utilized, the use of a more flexible needle, such as a nitinol 19-gauge (G) needle, has been recommended. The aim of this study was to evaluate the feasibility and accuracy of 19-G flexible aspiration needles in obtaining samples from solid lesions through a transduodenal approach. Methods This was a retrospective analysis of prospectively collected data from eight Italian endoscopy centers. Consecutive patients with solid lesions who underwent transduodenal EUS-FNA with a 19-G flexible needle were included. Results A total of 201 patients were enrolled. According to histology, EUS, radiology and 12 months of follow-up, 151 patients had malignant lesions and 50 patients had benign lesions. EUS-FNA was feasible in all cases. An adequate histologic sample was obtained in all except eight cases (96.1%). The sensitivity of EUS-FNA was 92.1% (95% confidence interval [CI], 86.8%–95.7%), and the specificity was 100% (95% CI, 90.5%–100%). The positive predictive value was 100% (95% CI, 93.4%–100%), and the negative predictive value was 74% (95% CI, 62.8%–82.7%). The diagnostic accuracy was 93.5% (95% CI, 89.2%–96.5%). Conclusions The transduodenal approach for obtaining samples from solid lesions using a 19-G flexible needle seems feasible and accurate.http://www.e-ce.org/upload/pdf/ce-2020-056.pdfendoscopic ultrasound-guided fine-needle aspirationendosonographyfeasibility studies |
| spellingShingle | Germana de Nucci Maria Chiara Petrone Nicola Imperatore Edoardo Forti Roberto Grassia Silvia Giovanelli Laura Ottaviani Vincenzo Mirante Giuseppe Sabatino Carlo Fabbri Mauro Manno Paolo Giorgio Arcidiacono Gianpiero Manes Feasibility and Accuracy of Transduodenal Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Solid Lesions Using a 19-Gauge Flexible Needle: A Multicenter Study Clinical Endoscopy endoscopic ultrasound-guided fine-needle aspiration endosonography feasibility studies |
| title | Feasibility and Accuracy of Transduodenal Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Solid Lesions Using a 19-Gauge Flexible Needle: A Multicenter Study |
| title_full | Feasibility and Accuracy of Transduodenal Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Solid Lesions Using a 19-Gauge Flexible Needle: A Multicenter Study |
| title_fullStr | Feasibility and Accuracy of Transduodenal Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Solid Lesions Using a 19-Gauge Flexible Needle: A Multicenter Study |
| title_full_unstemmed | Feasibility and Accuracy of Transduodenal Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Solid Lesions Using a 19-Gauge Flexible Needle: A Multicenter Study |
| title_short | Feasibility and Accuracy of Transduodenal Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Solid Lesions Using a 19-Gauge Flexible Needle: A Multicenter Study |
| title_sort | feasibility and accuracy of transduodenal endoscopic ultrasound guided fine needle aspiration of solid lesions using a 19 gauge flexible needle a multicenter study |
| topic | endoscopic ultrasound-guided fine-needle aspiration endosonography feasibility studies |
| url | http://www.e-ce.org/upload/pdf/ce-2020-056.pdf |
| work_keys_str_mv | AT germanadenucci feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT mariachiarapetrone feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT nicolaimperatore feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT edoardoforti feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT robertograssia feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT silviagiovanelli feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT lauraottaviani feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT vincenzomirante feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT giuseppesabatino feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT carlofabbri feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT mauromanno feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT paologiorgioarcidiacono feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy AT gianpieromanes feasibilityandaccuracyoftransduodenalendoscopicultrasoundguidedfineneedleaspirationofsolidlesionsusinga19gaugeflexibleneedleamulticenterstudy |