“Twin peaks”: Searching for 4-hydroxynonenal urinary metabolites after oral administration in rats

“Twin peaks”: Searching for 4-hydroxynonenal urinary metabolites after oral administration in rats

4-Hydroxynonenal (HNE) is a cytotoxic and genotoxic lipid oxidation secondary product which is formed endogenously upon peroxidation of cellular n-6 fatty acids. However, it can also be formed in food or during digestion, upon peroxidation of dietary lipids. Several studies have evidenced that we ar...

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Bibliographic Details
Main Authors:	Julia Keller, Maryse Baradat, Isabelle Jouanin, Laurent Debrauwer, Françoise Guéraud
Format:	Article
Language:	English
Published:	Elsevier 2015-04-01
Series:	Redox Biology
Subjects:	4-Hydroxynonenal Lipoperoxidation Metabolism HRMS Isotope tracking
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231714001402

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