Impact of fracture‐prone implantable cardioverter defibrillator leads on long‐term patient mortality
Abstract Background The long‐term relationship between fracture‐prone implantable cardioverter‐defibrillator (ICD) leads and poor prognosis remains unclear in Japanese patients. Methods We conducted a retrospective review of the records of 445 patients who underwent implantation of advisory/Linox le...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-06-01
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| Series: | Journal of Arrhythmia |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/joa3.12843 |
| _version_ | 1797804554725621760 |
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| author | Toshiharu Koike Morio Shoda Koichiro Ejima Daigo Yagishita Atsushi Suzuki Shun Hasegawa Shohei Kataoka Kyoichiro Yazaki Satoshi Higuchi Miwa Kanai Junichi Yamaguchi |
| author_facet | Toshiharu Koike Morio Shoda Koichiro Ejima Daigo Yagishita Atsushi Suzuki Shun Hasegawa Shohei Kataoka Kyoichiro Yazaki Satoshi Higuchi Miwa Kanai Junichi Yamaguchi |
| author_sort | Toshiharu Koike |
| collection | DOAJ |
| description | Abstract Background The long‐term relationship between fracture‐prone implantable cardioverter‐defibrillator (ICD) leads and poor prognosis remains unclear in Japanese patients. Methods We conducted a retrospective review of the records of 445 patients who underwent implantation of advisory/Linox leads (Sprint Fidelis, 118; Riata, nine; Isoline, 10; Linox S/SD, 45) and non‐advisory leads (Endotak Reliance, 33; Durata, 199; Sprint non‐Fidelis, 31) between January 2005 and June 2012 at our hospital. The primary outcomes were all‐cause mortality and ICD lead failure. The secondary outcomes were cardiovascular mortality, heart failure (HF) hospitalization, and the composite outcome of cardiovascular mortality and HF hospitalization. Results During the follow‐up period (median, 8.6 [4.1–12.0] years), there were 152 deaths: 61 (34%) in patients with advisory/Linox leads and 91 (35%) in those with non‐advisory leads. There were 32 ICD lead failures: 27 (15%) in patients with advisory/Linox leads and five (2%) in those with non‐advisory leads. Multivariate analysis for ICD lead failure demonstrated that the advisory/Linox leads had a 6.65‐fold significantly greater risk of ICD lead failure than non‐advisory leads. Congenital heart disease (hazard ratio 2.51; 95% confidence interval 1.08–5.83; p = .03) could also independently predict ICD lead failure. Multivariate analysis for all‐cause mortality demonstrated no significant association between advisory/Linox leads and all‐cause mortality. Conclusions Patients who have implanted fracture‐prone ICD leads should be carefully followed up for ICD lead failure. However, these patients have a long‐term survival rate comparable with that of patients with non‐advisory ICD leads in Japanese patients. |
| first_indexed | 2024-03-13T05:37:54Z |
| format | Article |
| id | doaj.art-c5d9cae62e0445cdadb7a727377bed50 |
| institution | Directory Open Access Journal |
| issn | 1880-4276 1883-2148 |
| language | English |
| last_indexed | 2024-03-13T05:37:54Z |
| publishDate | 2023-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Arrhythmia |
| spelling | doaj.art-c5d9cae62e0445cdadb7a727377bed502023-06-14T05:25:21ZengWileyJournal of Arrhythmia1880-42761883-21482023-06-0139345446310.1002/joa3.12843Impact of fracture‐prone implantable cardioverter defibrillator leads on long‐term patient mortalityToshiharu Koike0Morio Shoda1Koichiro Ejima2Daigo Yagishita3Atsushi Suzuki4Shun Hasegawa5Shohei Kataoka6Kyoichiro Yazaki7Satoshi Higuchi8Miwa Kanai9Junichi Yamaguchi10Department of Cardiology Tokyo Women's Medical University 8‐1 Kawada‐cho, Shinjuku‐ku Tokyo 162‐8666 JapanDepartment of Cardiology Tokyo Women's Medical University 8‐1 Kawada‐cho, Shinjuku‐ku Tokyo 162‐8666 JapanDepartment of Cardiology Tokyo Women's Medical University 8‐1 Kawada‐cho, Shinjuku‐ku Tokyo 162‐8666 JapanDepartment of Cardiology Tokyo Women's Medical University 8‐1 Kawada‐cho, Shinjuku‐ku Tokyo 162‐8666 JapanDepartment of Cardiology Tokyo Women's Medical University 8‐1 Kawada‐cho, Shinjuku‐ku Tokyo 162‐8666 JapanDepartment of Cardiology Tokyo Women's Medical University 8‐1 Kawada‐cho, Shinjuku‐ku Tokyo 162‐8666 JapanDepartment of Cardiology Tokyo Women's Medical University 8‐1 Kawada‐cho, Shinjuku‐ku Tokyo 162‐8666 JapanDepartment of Cardiology Tokyo Women's Medical University 8‐1 Kawada‐cho, Shinjuku‐ku Tokyo 162‐8666 JapanDepartment of Cardiology Tokyo Women's Medical University 8‐1 Kawada‐cho, Shinjuku‐ku Tokyo 162‐8666 JapanDepartment of Cardiology Tokyo Women's Medical University 8‐1 Kawada‐cho, Shinjuku‐ku Tokyo 162‐8666 JapanDepartment of Cardiology Tokyo Women's Medical University 8‐1 Kawada‐cho, Shinjuku‐ku Tokyo 162‐8666 JapanAbstract Background The long‐term relationship between fracture‐prone implantable cardioverter‐defibrillator (ICD) leads and poor prognosis remains unclear in Japanese patients. Methods We conducted a retrospective review of the records of 445 patients who underwent implantation of advisory/Linox leads (Sprint Fidelis, 118; Riata, nine; Isoline, 10; Linox S/SD, 45) and non‐advisory leads (Endotak Reliance, 33; Durata, 199; Sprint non‐Fidelis, 31) between January 2005 and June 2012 at our hospital. The primary outcomes were all‐cause mortality and ICD lead failure. The secondary outcomes were cardiovascular mortality, heart failure (HF) hospitalization, and the composite outcome of cardiovascular mortality and HF hospitalization. Results During the follow‐up period (median, 8.6 [4.1–12.0] years), there were 152 deaths: 61 (34%) in patients with advisory/Linox leads and 91 (35%) in those with non‐advisory leads. There were 32 ICD lead failures: 27 (15%) in patients with advisory/Linox leads and five (2%) in those with non‐advisory leads. Multivariate analysis for ICD lead failure demonstrated that the advisory/Linox leads had a 6.65‐fold significantly greater risk of ICD lead failure than non‐advisory leads. Congenital heart disease (hazard ratio 2.51; 95% confidence interval 1.08–5.83; p = .03) could also independently predict ICD lead failure. Multivariate analysis for all‐cause mortality demonstrated no significant association between advisory/Linox leads and all‐cause mortality. Conclusions Patients who have implanted fracture‐prone ICD leads should be carefully followed up for ICD lead failure. However, these patients have a long‐term survival rate comparable with that of patients with non‐advisory ICD leads in Japanese patients.https://doi.org/10.1002/joa3.12843advisory leadimplantable cardioverter‐defibrillator leadlead failureLinoxmortality |
| spellingShingle | Toshiharu Koike Morio Shoda Koichiro Ejima Daigo Yagishita Atsushi Suzuki Shun Hasegawa Shohei Kataoka Kyoichiro Yazaki Satoshi Higuchi Miwa Kanai Junichi Yamaguchi Impact of fracture‐prone implantable cardioverter defibrillator leads on long‐term patient mortality Journal of Arrhythmia advisory lead implantable cardioverter‐defibrillator lead lead failure Linox mortality |
| title | Impact of fracture‐prone implantable cardioverter defibrillator leads on long‐term patient mortality |
| title_full | Impact of fracture‐prone implantable cardioverter defibrillator leads on long‐term patient mortality |
| title_fullStr | Impact of fracture‐prone implantable cardioverter defibrillator leads on long‐term patient mortality |
| title_full_unstemmed | Impact of fracture‐prone implantable cardioverter defibrillator leads on long‐term patient mortality |
| title_short | Impact of fracture‐prone implantable cardioverter defibrillator leads on long‐term patient mortality |
| title_sort | impact of fracture prone implantable cardioverter defibrillator leads on long term patient mortality |
| topic | advisory lead implantable cardioverter‐defibrillator lead lead failure Linox mortality |
| url | https://doi.org/10.1002/joa3.12843 |
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