A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging
The synthesis of 6-(2,5-dimethoxy-4-(2-aminopropyl)phenyl)hexylthiol, an agonist with a very high affinity for the 5HT2A serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulfide core/shells via a thiol at the end of a linker...
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MDPI AG
2002-11-01
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Series: | Molecules |
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Online Access: | http://www.mdpi.com/1420-3049/7/11/777/ |
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author | Sandra J. Rosenthal Jesse L. Grey Ian D. Tomlinson |
author_facet | Sandra J. Rosenthal Jesse L. Grey Ian D. Tomlinson |
author_sort | Sandra J. Rosenthal |
collection | DOAJ |
description | The synthesis of 6-(2,5-dimethoxy-4-(2-aminopropyl)phenyl)hexylthiol, an agonist with a very high affinity for the 5HT2A serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulfide core/shells via a thiol at the end of a linker arm. This conjugate has applications in biological assays and biological imaging. |
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id | doaj.art-c5daaaa4e0c84610b7a4d5912870011d |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-12-21T12:56:57Z |
publishDate | 2002-11-01 |
publisher | MDPI AG |
record_format | Article |
series | Molecules |
spelling | doaj.art-c5daaaa4e0c84610b7a4d5912870011d2022-12-21T19:03:18ZengMDPI AGMolecules1420-30492002-11-0171177779010.3390/71100777A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological ImagingSandra J. RosenthalJesse L. GreyIan D. TomlinsonThe synthesis of 6-(2,5-dimethoxy-4-(2-aminopropyl)phenyl)hexylthiol, an agonist with a very high affinity for the 5HT2A serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulfide core/shells via a thiol at the end of a linker arm. This conjugate has applications in biological assays and biological imaging.http://www.mdpi.com/1420-3049/7/11/777/Cadmium selenide / zinc sulfide / core/shells / 5HT2A / fluorescent imaging |
spellingShingle | Sandra J. Rosenthal Jesse L. Grey Ian D. Tomlinson A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging Molecules Cadmium selenide / zinc sulfide / core/shells / 5HT2A / fluorescent imaging |
title | A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging |
title_full | A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging |
title_fullStr | A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging |
title_full_unstemmed | A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging |
title_short | A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging |
title_sort | synthesis of 6 2 5 dimethoxy 4 2 aminopropyl phenyl hexylthiol a ligand for conjugation with fluorescent cadmium selenide zinc sulfide core shell nanocrystals and biological imaging |
topic | Cadmium selenide / zinc sulfide / core/shells / 5HT2A / fluorescent imaging |
url | http://www.mdpi.com/1420-3049/7/11/777/ |
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