A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging

The synthesis of 6-(2,5-dimethoxy-4-(2-aminopropyl)phenyl)hexylthiol, an agonist with a very high affinity for the 5HT2A serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulfide core/shells via a thiol at the end of a linker...

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Main Authors: Sandra J. Rosenthal, Jesse L. Grey, Ian D. Tomlinson
Format: Article
Language:English
Published: MDPI AG 2002-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/7/11/777/
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author Sandra J. Rosenthal
Jesse L. Grey
Ian D. Tomlinson
author_facet Sandra J. Rosenthal
Jesse L. Grey
Ian D. Tomlinson
author_sort Sandra J. Rosenthal
collection DOAJ
description The synthesis of 6-(2,5-dimethoxy-4-(2-aminopropyl)phenyl)hexylthiol, an agonist with a very high affinity for the 5HT2A serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulfide core/shells via a thiol at the end of a linker arm. This conjugate has applications in biological assays and biological imaging.
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spelling doaj.art-c5daaaa4e0c84610b7a4d5912870011d2022-12-21T19:03:18ZengMDPI AGMolecules1420-30492002-11-0171177779010.3390/71100777A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological ImagingSandra J. RosenthalJesse L. GreyIan D. TomlinsonThe synthesis of 6-(2,5-dimethoxy-4-(2-aminopropyl)phenyl)hexylthiol, an agonist with a very high affinity for the 5HT2A serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulfide core/shells via a thiol at the end of a linker arm. This conjugate has applications in biological assays and biological imaging.http://www.mdpi.com/1420-3049/7/11/777/Cadmium selenide / zinc sulfide / core/shells / 5HT2A / fluorescent imaging
spellingShingle Sandra J. Rosenthal
Jesse L. Grey
Ian D. Tomlinson
A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging
Molecules
Cadmium selenide / zinc sulfide / core/shells / 5HT2A / fluorescent imaging
title A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging
title_full A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging
title_fullStr A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging
title_full_unstemmed A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging
title_short A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging
title_sort synthesis of 6 2 5 dimethoxy 4 2 aminopropyl phenyl hexylthiol a ligand for conjugation with fluorescent cadmium selenide zinc sulfide core shell nanocrystals and biological imaging
topic Cadmium selenide / zinc sulfide / core/shells / 5HT2A / fluorescent imaging
url http://www.mdpi.com/1420-3049/7/11/777/
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