Multiple metals influence distinct properties of the Arabidopsis circadian clock.
Circadian rhythms coordinate endogenous events with external signals, and are essential to biological function. When environmental contaminants affect these rhythms, the organism may experience fitness consequences such as reduced growth or increased susceptibility to pathogens. In their natural env...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0258374 |
| _version_ | 1811288689183031296 |
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| author | Jessica K Hargreaves Rachael J Oakenfull Amanda M Davis Freya Pullen Marina I Knight Jon W Pitchford Seth J Davis |
| author_facet | Jessica K Hargreaves Rachael J Oakenfull Amanda M Davis Freya Pullen Marina I Knight Jon W Pitchford Seth J Davis |
| author_sort | Jessica K Hargreaves |
| collection | DOAJ |
| description | Circadian rhythms coordinate endogenous events with external signals, and are essential to biological function. When environmental contaminants affect these rhythms, the organism may experience fitness consequences such as reduced growth or increased susceptibility to pathogens. In their natural environment plants may be exposed to a wide range of industrial and agricultural soil pollutants. Here, we investigate how the addition of various metal salts to the root-interaction environment can impact rhythms, measured via the promoter:luciferase system. The consequences of these environmental changes were found to be varied and complex. Therefore, in addition to traditional Fourier-based analyses, we additionally apply novel wavelet-based spectral hypothesis testing and clustering methodologies to organize and understand the data. We are able to classify broad sets of responses to these metal salts, including those that increase, and those that decrease, the period, or which induce a lack of precision or disrupt any meaningful periodicity. Our methods are general, and may be applied to discover common responses and hidden structures within a wide range of biological time series data. |
| first_indexed | 2024-04-13T03:41:41Z |
| format | Article |
| id | doaj.art-c5dee1ff2c5046929c2b447703b3128f |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T03:41:41Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-c5dee1ff2c5046929c2b447703b3128f2022-12-22T03:04:08ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01174e025837410.1371/journal.pone.0258374Multiple metals influence distinct properties of the Arabidopsis circadian clock.Jessica K HargreavesRachael J OakenfullAmanda M DavisFreya PullenMarina I KnightJon W PitchfordSeth J DavisCircadian rhythms coordinate endogenous events with external signals, and are essential to biological function. When environmental contaminants affect these rhythms, the organism may experience fitness consequences such as reduced growth or increased susceptibility to pathogens. In their natural environment plants may be exposed to a wide range of industrial and agricultural soil pollutants. Here, we investigate how the addition of various metal salts to the root-interaction environment can impact rhythms, measured via the promoter:luciferase system. The consequences of these environmental changes were found to be varied and complex. Therefore, in addition to traditional Fourier-based analyses, we additionally apply novel wavelet-based spectral hypothesis testing and clustering methodologies to organize and understand the data. We are able to classify broad sets of responses to these metal salts, including those that increase, and those that decrease, the period, or which induce a lack of precision or disrupt any meaningful periodicity. Our methods are general, and may be applied to discover common responses and hidden structures within a wide range of biological time series data.https://doi.org/10.1371/journal.pone.0258374 |
| spellingShingle | Jessica K Hargreaves Rachael J Oakenfull Amanda M Davis Freya Pullen Marina I Knight Jon W Pitchford Seth J Davis Multiple metals influence distinct properties of the Arabidopsis circadian clock. PLoS ONE |
| title | Multiple metals influence distinct properties of the Arabidopsis circadian clock. |
| title_full | Multiple metals influence distinct properties of the Arabidopsis circadian clock. |
| title_fullStr | Multiple metals influence distinct properties of the Arabidopsis circadian clock. |
| title_full_unstemmed | Multiple metals influence distinct properties of the Arabidopsis circadian clock. |
| title_short | Multiple metals influence distinct properties of the Arabidopsis circadian clock. |
| title_sort | multiple metals influence distinct properties of the arabidopsis circadian clock |
| url | https://doi.org/10.1371/journal.pone.0258374 |
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