Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis

Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave...

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Bibliographic Details
Main Authors: Tristan Mangeolle, Ilya Yakavets, Sophie Marchal, Manon Debayle, Thomas Pons, Lina Bezdetnaya, Frédéric Marchal
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Nanomaterials
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Online Access:http://www.mdpi.com/2079-4991/8/8/572
Description
Summary:Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave infrared fluorescent nanoparticles, which are currently under investigation for peritoneal carcinomatosis fluorescence imaging. We also highlight the main ways to improve the safety of nanoparticles, for fulfilling prerequisites of clinical application.
ISSN:2079-4991