A 10-Year Retrospective Study of Inclusion Body Hepatitis in Meat-Type Chickens in Spain (2011–2021)
A surge in fowl adenovirus (FAdV) causing inclusion body hepatitis (IBH) outbreaks has occurred in several countries in the last two decades. In Spain, a sharp increase in case numbers in broilers and broiler breeder pullets arose since 2011, which prompted the vaccination of breeders in some region...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/13/11/2170 |
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| author | Kateri Bertran Angela Blanco Noelia Antilles Miquel Nofrarías Rosa M. Valle Àlex Cobos Antonio Ramis Mar Biarnés Natàlia Majó |
| author_facet | Kateri Bertran Angela Blanco Noelia Antilles Miquel Nofrarías Rosa M. Valle Àlex Cobos Antonio Ramis Mar Biarnés Natàlia Majó |
| author_sort | Kateri Bertran |
| collection | DOAJ |
| description | A surge in fowl adenovirus (FAdV) causing inclusion body hepatitis (IBH) outbreaks has occurred in several countries in the last two decades. In Spain, a sharp increase in case numbers in broilers and broiler breeder pullets arose since 2011, which prompted the vaccination of breeders in some regions. Our retrospective study of IBH cases in Spain from 2011 to 2021 revealed that most cases were reported in broilers (92.21%) and were caused by serotypes FAdV-8b and -11, while cases in broiler breeder pullets were caused by serotypes FAdV-2, -11, and -8b. Vertical transmission was the main route of infection, although horizontal transmission likely happened in some broiler cases. Despite the inconsistent and heterogeneous use of vaccines among regions and over time, the number of cases mirrored the use of vaccines in the country. While IBH outbreaks were recorded year-long, significantly more cases occurred during the cooler and rainier months. The geographic distribution suggested a widespread incidence of IBH and revealed the importance of a highly integrated system. Our findings contribute to a better understanding of FAdV infection dynamics under field conditions and reiterate the importance of surveillance, serological monitoring of breeders, and vaccination of breeders against circulating serotypes to protect progenies. |
| first_indexed | 2024-03-10T04:59:32Z |
| format | Article |
| id | doaj.art-c5e409ee7d0741c092cd09730e9e2b72 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T04:59:32Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-c5e409ee7d0741c092cd09730e9e2b722023-11-23T01:56:03ZengMDPI AGViruses1999-49152021-10-011311217010.3390/v13112170A 10-Year Retrospective Study of Inclusion Body Hepatitis in Meat-Type Chickens in Spain (2011–2021)Kateri Bertran0Angela Blanco1Noelia Antilles2Miquel Nofrarías3Rosa M. Valle4Àlex Cobos5Antonio Ramis6Mar Biarnés7Natàlia Majó8IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, SpainCentre de Sanitat Avícola de Catalunya i Aragó (CESAC), 43206 Reus, SpainCentre de Sanitat Avícola de Catalunya i Aragó (CESAC), 43206 Reus, SpainIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, SpainIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, SpainIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, SpainIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, SpainCentre de Sanitat Avícola de Catalunya i Aragó (CESAC), 43206 Reus, SpainIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, SpainA surge in fowl adenovirus (FAdV) causing inclusion body hepatitis (IBH) outbreaks has occurred in several countries in the last two decades. In Spain, a sharp increase in case numbers in broilers and broiler breeder pullets arose since 2011, which prompted the vaccination of breeders in some regions. Our retrospective study of IBH cases in Spain from 2011 to 2021 revealed that most cases were reported in broilers (92.21%) and were caused by serotypes FAdV-8b and -11, while cases in broiler breeder pullets were caused by serotypes FAdV-2, -11, and -8b. Vertical transmission was the main route of infection, although horizontal transmission likely happened in some broiler cases. Despite the inconsistent and heterogeneous use of vaccines among regions and over time, the number of cases mirrored the use of vaccines in the country. While IBH outbreaks were recorded year-long, significantly more cases occurred during the cooler and rainier months. The geographic distribution suggested a widespread incidence of IBH and revealed the importance of a highly integrated system. Our findings contribute to a better understanding of FAdV infection dynamics under field conditions and reiterate the importance of surveillance, serological monitoring of breeders, and vaccination of breeders against circulating serotypes to protect progenies.https://www.mdpi.com/1999-4915/13/11/2170fowl adenovirusinclusion body hepatitisSpainepidemiologybroilersbroiler breeder pullets |
| spellingShingle | Kateri Bertran Angela Blanco Noelia Antilles Miquel Nofrarías Rosa M. Valle Àlex Cobos Antonio Ramis Mar Biarnés Natàlia Majó A 10-Year Retrospective Study of Inclusion Body Hepatitis in Meat-Type Chickens in Spain (2011–2021) Viruses fowl adenovirus inclusion body hepatitis Spain epidemiology broilers broiler breeder pullets |
| title | A 10-Year Retrospective Study of Inclusion Body Hepatitis in Meat-Type Chickens in Spain (2011–2021) |
| title_full | A 10-Year Retrospective Study of Inclusion Body Hepatitis in Meat-Type Chickens in Spain (2011–2021) |
| title_fullStr | A 10-Year Retrospective Study of Inclusion Body Hepatitis in Meat-Type Chickens in Spain (2011–2021) |
| title_full_unstemmed | A 10-Year Retrospective Study of Inclusion Body Hepatitis in Meat-Type Chickens in Spain (2011–2021) |
| title_short | A 10-Year Retrospective Study of Inclusion Body Hepatitis in Meat-Type Chickens in Spain (2011–2021) |
| title_sort | 10 year retrospective study of inclusion body hepatitis in meat type chickens in spain 2011 2021 |
| topic | fowl adenovirus inclusion body hepatitis Spain epidemiology broilers broiler breeder pullets |
| url | https://www.mdpi.com/1999-4915/13/11/2170 |
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