A rare entity of Primary Ewing sarcoma in kidney
Abstract Background Ewing sarcoma (ES) or primitive neuroectodermal tumors (PNET) represents a spectrum of poorly differentiated and aggressive malignancies. It rarely arises from the kidney and accounts for less than 1% of renal mass. Given the uncharacteristic clinical symptoms and imaging feature...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-11-01
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| Series: | BMC Surgery |
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| Online Access: | http://link.springer.com/article/10.1186/s12893-020-00948-9 |
| _version_ | 1818268745995386880 |
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| author | Li Cheng Yujie Xu Hong Song Houbao Huang Dong Zhuo |
| author_facet | Li Cheng Yujie Xu Hong Song Houbao Huang Dong Zhuo |
| author_sort | Li Cheng |
| collection | DOAJ |
| description | Abstract Background Ewing sarcoma (ES) or primitive neuroectodermal tumors (PNET) represents a spectrum of poorly differentiated and aggressive malignancies. It rarely arises from the kidney and accounts for less than 1% of renal mass. Given the uncharacteristic clinical symptoms and imaging features, renal Ewing sarcoma (RES) is often diagnosed by postoperative pathology. Case presentation Herein, we depicted a case of RES, which was administrated in our institution by chief complaints of intermittent left plank pain and palpable abdominal mass. We demonstrated the aggressive behavior of this renal malignancy and summarized its therapeutic modalities and outcomes. Conclusion The diagnosis of RES relies on integrated analysis including histomorphology, immunohistochemical staining and confirmation of molecular-genetic testing. Despite the surgery and adjuvant therapy, optimized and potent therapeutic regimes are still urgently needed to improve the poor prognosis of RES. |
| first_indexed | 2024-12-12T20:43:23Z |
| format | Article |
| id | doaj.art-c5e42d76055c40eb8deef75bb9f5da11 |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-12-12T20:43:23Z |
| publishDate | 2020-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-c5e42d76055c40eb8deef75bb9f5da112022-12-22T00:12:39ZengBMCBMC Surgery1471-24822020-11-012011510.1186/s12893-020-00948-9A rare entity of Primary Ewing sarcoma in kidneyLi Cheng0Yujie Xu1Hong Song2Houbao Huang3Dong Zhuo4Department of Urology, Anhui Province, The First Affiliated Hospital of Wannan Medical CollegeDepartment of Urology, Anhui Province, The First Affiliated Hospital of Wannan Medical CollegeDepartment of Pathology, Anhui Province, The First Affiliated Hospital of Wannan Medical CollegeDepartment of Urology, Anhui Province, The First Affiliated Hospital of Wannan Medical CollegeDepartment of Urology, Anhui Province, The First Affiliated Hospital of Wannan Medical CollegeAbstract Background Ewing sarcoma (ES) or primitive neuroectodermal tumors (PNET) represents a spectrum of poorly differentiated and aggressive malignancies. It rarely arises from the kidney and accounts for less than 1% of renal mass. Given the uncharacteristic clinical symptoms and imaging features, renal Ewing sarcoma (RES) is often diagnosed by postoperative pathology. Case presentation Herein, we depicted a case of RES, which was administrated in our institution by chief complaints of intermittent left plank pain and palpable abdominal mass. We demonstrated the aggressive behavior of this renal malignancy and summarized its therapeutic modalities and outcomes. Conclusion The diagnosis of RES relies on integrated analysis including histomorphology, immunohistochemical staining and confirmation of molecular-genetic testing. Despite the surgery and adjuvant therapy, optimized and potent therapeutic regimes are still urgently needed to improve the poor prognosis of RES.http://link.springer.com/article/10.1186/s12893-020-00948-9Renal ewing sarcoma (RES)Primitive neuroectodermal tumor (PNET)NephrectomyChemotherapy |
| spellingShingle | Li Cheng Yujie Xu Hong Song Houbao Huang Dong Zhuo A rare entity of Primary Ewing sarcoma in kidney BMC Surgery Renal ewing sarcoma (RES) Primitive neuroectodermal tumor (PNET) Nephrectomy Chemotherapy |
| title | A rare entity of Primary Ewing sarcoma in kidney |
| title_full | A rare entity of Primary Ewing sarcoma in kidney |
| title_fullStr | A rare entity of Primary Ewing sarcoma in kidney |
| title_full_unstemmed | A rare entity of Primary Ewing sarcoma in kidney |
| title_short | A rare entity of Primary Ewing sarcoma in kidney |
| title_sort | rare entity of primary ewing sarcoma in kidney |
| topic | Renal ewing sarcoma (RES) Primitive neuroectodermal tumor (PNET) Nephrectomy Chemotherapy |
| url | http://link.springer.com/article/10.1186/s12893-020-00948-9 |
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