Case Report: Primary Thoracic Low-Grade Fibromyxoid Sarcoma in a Young Girl Presenting With Mediastinal Mass Syndrome
Low-grade fibromyxoid sarcomas (LGFMSs) are typically adult-onset tumors that arise from the extremities. Here, we report an exceptional case of primary thoracic LGFMS in an 8-year-old girl that resulted in mediastinal syndrome. In reporting this case, we discuss the clinical challenges, role of mol...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.885068/full |
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| author | Yat Chi Chan Amanda N. C. Kan Liz Y. P. Yuen Innes Y. P. Wan Kevin K. F. Fung Yiu-fai Cheung Yiu-fai Cheung Karen K. Y. Leung Dennis T. L. Ku Anthony P. Y. Liu Anthony P. Y. Liu |
| author_facet | Yat Chi Chan Amanda N. C. Kan Liz Y. P. Yuen Innes Y. P. Wan Kevin K. F. Fung Yiu-fai Cheung Yiu-fai Cheung Karen K. Y. Leung Dennis T. L. Ku Anthony P. Y. Liu Anthony P. Y. Liu |
| author_sort | Yat Chi Chan |
| collection | DOAJ |
| description | Low-grade fibromyxoid sarcomas (LGFMSs) are typically adult-onset tumors that arise from the extremities. Here, we report an exceptional case of primary thoracic LGFMS in an 8-year-old girl that resulted in mediastinal syndrome. In reporting this case, we discuss the clinical challenges, role of molecular profiling and review reported cases of pediatric thoracic LGFMSs. |
| first_indexed | 2024-04-12T14:38:22Z |
| format | Article |
| id | doaj.art-c5e55f106c0241419ba189a8a3ecec06 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-12T14:38:22Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-c5e55f106c0241419ba189a8a3ecec062022-12-22T03:29:00ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-06-011010.3389/fped.2022.885068885068Case Report: Primary Thoracic Low-Grade Fibromyxoid Sarcoma in a Young Girl Presenting With Mediastinal Mass SyndromeYat Chi Chan0Amanda N. C. Kan1Liz Y. P. Yuen2Innes Y. P. Wan3Kevin K. F. Fung4Yiu-fai Cheung5Yiu-fai Cheung6Karen K. Y. Leung7Dennis T. L. Ku8Anthony P. Y. Liu9Anthony P. Y. Liu10LKS Faculty of Medicine, The University of Hong Kong, Kowloon, Hong Kong SAR, ChinaDepartment of Pathology, Hong Kong Children’s Hospital, Kowloon, Hong Kong SAR, ChinaDivision of Genetic and Genomic Pathology, Department of Pathology, Hong Kong Children’s Hospital, Kowloon, Hong Kong SAR, ChinaDepartment of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, ChinaDepartment of Radiology, Hong Kong Children’s Hospital, Kowloon, Hong Kong SAR, ChinaDepartment of Paediatrics and Adolescent Medicine, Hong Kong Children’s Hospital, Kowloon, Hong Kong SAR, ChinaDepartment of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Kowloon, Hong Kong SAR, ChinaDepartment of Paediatrics and Adolescent Medicine, Hong Kong Children’s Hospital, Kowloon, Hong Kong SAR, ChinaDepartment of Paediatrics and Adolescent Medicine, Hong Kong Children’s Hospital, Kowloon, Hong Kong SAR, ChinaDepartment of Paediatrics and Adolescent Medicine, Hong Kong Children’s Hospital, Kowloon, Hong Kong SAR, ChinaDepartment of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Kowloon, Hong Kong SAR, ChinaLow-grade fibromyxoid sarcomas (LGFMSs) are typically adult-onset tumors that arise from the extremities. Here, we report an exceptional case of primary thoracic LGFMS in an 8-year-old girl that resulted in mediastinal syndrome. In reporting this case, we discuss the clinical challenges, role of molecular profiling and review reported cases of pediatric thoracic LGFMSs.https://www.frontiersin.org/articles/10.3389/fped.2022.885068/fulllow-grade fibromyxoid sarcomathoracic tumorpediatricsmediastinal syndromeRNA-sequencing |
| spellingShingle | Yat Chi Chan Amanda N. C. Kan Liz Y. P. Yuen Innes Y. P. Wan Kevin K. F. Fung Yiu-fai Cheung Yiu-fai Cheung Karen K. Y. Leung Dennis T. L. Ku Anthony P. Y. Liu Anthony P. Y. Liu Case Report: Primary Thoracic Low-Grade Fibromyxoid Sarcoma in a Young Girl Presenting With Mediastinal Mass Syndrome Frontiers in Pediatrics low-grade fibromyxoid sarcoma thoracic tumor pediatrics mediastinal syndrome RNA-sequencing |
| title | Case Report: Primary Thoracic Low-Grade Fibromyxoid Sarcoma in a Young Girl Presenting With Mediastinal Mass Syndrome |
| title_full | Case Report: Primary Thoracic Low-Grade Fibromyxoid Sarcoma in a Young Girl Presenting With Mediastinal Mass Syndrome |
| title_fullStr | Case Report: Primary Thoracic Low-Grade Fibromyxoid Sarcoma in a Young Girl Presenting With Mediastinal Mass Syndrome |
| title_full_unstemmed | Case Report: Primary Thoracic Low-Grade Fibromyxoid Sarcoma in a Young Girl Presenting With Mediastinal Mass Syndrome |
| title_short | Case Report: Primary Thoracic Low-Grade Fibromyxoid Sarcoma in a Young Girl Presenting With Mediastinal Mass Syndrome |
| title_sort | case report primary thoracic low grade fibromyxoid sarcoma in a young girl presenting with mediastinal mass syndrome |
| topic | low-grade fibromyxoid sarcoma thoracic tumor pediatrics mediastinal syndrome RNA-sequencing |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.885068/full |
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