The Phenotype and Treatment of WIP Deficiency: Literature Synopsis and Review of a Patient With Pre-transplant Serial Donor Lymphocyte Infusions to Eliminate CMV

The Phenotype and Treatment of WIP Deficiency: Literature Synopsis and Review of a Patient With Pre-transplant Serial Donor Lymphocyte Infusions to Eliminate CMV

Early diagnosis of primary immunodeficiency disorders (PID) is vital and allows directed treatment, especially in syndromes with severe or profound combined immunodeficiency. In PID patients with perinatal CMV or other opportunistic, invasive infections (e.g., Pneumocystis or Aspergillus), multi-org...

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Bibliographic Details
Main Authors: Wolfgang Schwinger, Christian Urban, Raphael Ulreich, Daniela Sperl, Anna Karastaneva, Volker Strenger, Herwig Lackner, Kaan Boztug, Michael H. Albert, Martin Benesch, Markus G. Seidel
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
Wiskott-Aldrich syndrome protein-interacting protein (WIP)
primary immunodeficiency (PID)
Wiskott-Aldrich syndrome (WAS)
hematopoietic stem cell transplantation (HSCT)
donor lymphocyte infusions (DLI)
combined immunodeficiency (CID) with syndromic features
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02554/full

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