Inhibition of TRPC6 Signal Pathway Alleviates Podocyte Injury Induced by TGF-β1

Inhibition of TRPC6 Signal Pathway Alleviates Podocyte Injury Induced by TGF-β1

Background/Aims: Transforming growth factor beta 1 (TGF-β1) plays a critical role in the pathogenesis of glomerulosclerosis. The purpose of this study was to examine the effects of inhibition of transient receptor potential cation channel C6 (TRPC6) on podocyte injury induced by TGF-β1 via nephrin a...

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Bibliographic Details
Main Authors: Haiting Huang, Yanwu You, Xu Lin, Chunrong Tang, Xiangjun Gu, Meiying Huang, Youling Qin, Junhua Tan, Feifan Huang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Podocytes
TGF-β1
TRPC6
Nephrin
Desmin
Caspase 9
Online Access:http://www.karger.com/Article/FullText/455985

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