A universal approach to eliminate antigenic properties of alpha-gliadin peptides in celiac disease.

A universal approach to eliminate antigenic properties of alpha-gliadin peptides in celiac disease.

Celiac disease is caused by an uncontrolled immune response to gluten, a heterogeneous mixture of wheat storage proteins, including the α-gliadins. It has been shown that α-gliadins harbor several major epitopes involved in the disease pathogenesis. A major step towards elimination of gluten toxicit...

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Bibliographic Details
Main Authors:	Cristina Mitea, Elma M J Salentijn, Peter van Veelen, Svetlana V Goryunova, Ingrid M van der Meer, Hetty C van den Broeck, Jorge R Mujico, Veronica Montserrat, Luud J W J Gilissen, Jan Wouter Drijfhout, Liesbeth Dekking, Frits Koning, Marinus J M Smulders
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3002971?pdf=render

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