Heated Corn Oil and 2,4-Decadienal Suppress Gastric Emptying and Energy Intake in Humans
Consumption of 2,4-decadienal (2,4-DD) delays gastric emptying (GE) rate in animals. Oil heating produces 2,4-DD and other aldehydes. Here we examined whether heated oil affects GE rate and food intake in humans, and whether it is mediated by 2,4-DD. In the first experiment, 10 healthy volunteers co...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-04-01
|
| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/13/4/1304 |
| _version_ | 1797537612799410176 |
|---|---|
| author | Hideaki Kashima Ayumi Honma Saori Kamimura Saki Nishimura Takashi Sano Shoji Matsumoto Masako Yamaoka Endo Yoshiyuki Fukuba |
| author_facet | Hideaki Kashima Ayumi Honma Saori Kamimura Saki Nishimura Takashi Sano Shoji Matsumoto Masako Yamaoka Endo Yoshiyuki Fukuba |
| author_sort | Hideaki Kashima |
| collection | DOAJ |
| description | Consumption of 2,4-decadienal (2,4-DD) delays gastric emptying (GE) rate in animals. Oil heating produces 2,4-DD and other aldehydes. Here we examined whether heated oil affects GE rate and food intake in humans, and whether it is mediated by 2,4-DD. In the first experiment, 10 healthy volunteers consumed 240-g pumpkin soup with 9.2 g of heated (HO) or non-heated corn oil (CO). Subsequently, 17 participants consumed pumpkin soup containing 3.1 g of either heated corn oil (HO), 1 mg 2,4-DD + non-heated corn oil (2,4-DD), or non-heated corn oil (CO). Sixty minutes following pumpkin soup, cod roe spaghetti was provided, and then energy intake was determined. To evaluate GE rate, <sup>13</sup>C breath test (Experiment 1) and ultrasonography (Experiments 1 and 2) were used. The results from the Experiment 1 confirmed that consumption of heated corn oil reduced GE rate. Experiment 2 showed a delayed GE rate in HO and 2,4-DD trials compared with CO trial (<i>p</i> < 0.05). Energy intake was approximately 600–650 kJ lower in HO and 2,4-DD trials compared with CO trial (<i>p</i> < 0.05). These findings suggest that 2,4-DD, either formed by oil heating or added to food, contributes to suppressing GE rate and energy intake. |
| first_indexed | 2024-03-10T12:18:42Z |
| format | Article |
| id | doaj.art-c5f063cc85dd4746a6a5e953296132b8 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T12:18:42Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-c5f063cc85dd4746a6a5e953296132b82023-11-21T15:40:29ZengMDPI AGNutrients2072-66432021-04-01134130410.3390/nu13041304Heated Corn Oil and 2,4-Decadienal Suppress Gastric Emptying and Energy Intake in HumansHideaki Kashima0Ayumi Honma1Saori Kamimura2Saki Nishimura3Takashi Sano4Shoji Matsumoto5Masako Yamaoka Endo6Yoshiyuki Fukuba7School of Health Sciences, Prefectural University of Hiroshima, 1-1-71 Ujina-higashi, Minami-ku, Hiroshima 734-8558, JapanSchool of Health Sciences, Prefectural University of Hiroshima, 1-1-71 Ujina-higashi, Minami-ku, Hiroshima 734-8558, JapanSchool of Health Sciences, Prefectural University of Hiroshima, 1-1-71 Ujina-higashi, Minami-ku, Hiroshima 734-8558, JapanJ-Oil Mills, Inc., 7-41 Oogurocho, Tsurumi-ku, Yokohama 230-0053, JapanJ-Oil Mills, Inc., 7-41 Oogurocho, Tsurumi-ku, Yokohama 230-0053, JapanJ-Oil Mills, Inc., 7-41 Oogurocho, Tsurumi-ku, Yokohama 230-0053, JapanSchool of Health Sciences, Prefectural University of Hiroshima, 1-1-71 Ujina-higashi, Minami-ku, Hiroshima 734-8558, JapanSchool of Health Sciences, Prefectural University of Hiroshima, 1-1-71 Ujina-higashi, Minami-ku, Hiroshima 734-8558, JapanConsumption of 2,4-decadienal (2,4-DD) delays gastric emptying (GE) rate in animals. Oil heating produces 2,4-DD and other aldehydes. Here we examined whether heated oil affects GE rate and food intake in humans, and whether it is mediated by 2,4-DD. In the first experiment, 10 healthy volunteers consumed 240-g pumpkin soup with 9.2 g of heated (HO) or non-heated corn oil (CO). Subsequently, 17 participants consumed pumpkin soup containing 3.1 g of either heated corn oil (HO), 1 mg 2,4-DD + non-heated corn oil (2,4-DD), or non-heated corn oil (CO). Sixty minutes following pumpkin soup, cod roe spaghetti was provided, and then energy intake was determined. To evaluate GE rate, <sup>13</sup>C breath test (Experiment 1) and ultrasonography (Experiments 1 and 2) were used. The results from the Experiment 1 confirmed that consumption of heated corn oil reduced GE rate. Experiment 2 showed a delayed GE rate in HO and 2,4-DD trials compared with CO trial (<i>p</i> < 0.05). Energy intake was approximately 600–650 kJ lower in HO and 2,4-DD trials compared with CO trial (<i>p</i> < 0.05). These findings suggest that 2,4-DD, either formed by oil heating or added to food, contributes to suppressing GE rate and energy intake.https://www.mdpi.com/2072-6643/13/4/1304gastric emptying ratefood intakeenergy intakeoil2,4-decadienalappetite |
| spellingShingle | Hideaki Kashima Ayumi Honma Saori Kamimura Saki Nishimura Takashi Sano Shoji Matsumoto Masako Yamaoka Endo Yoshiyuki Fukuba Heated Corn Oil and 2,4-Decadienal Suppress Gastric Emptying and Energy Intake in Humans Nutrients gastric emptying rate food intake energy intake oil 2,4-decadienal appetite |
| title | Heated Corn Oil and 2,4-Decadienal Suppress Gastric Emptying and Energy Intake in Humans |
| title_full | Heated Corn Oil and 2,4-Decadienal Suppress Gastric Emptying and Energy Intake in Humans |
| title_fullStr | Heated Corn Oil and 2,4-Decadienal Suppress Gastric Emptying and Energy Intake in Humans |
| title_full_unstemmed | Heated Corn Oil and 2,4-Decadienal Suppress Gastric Emptying and Energy Intake in Humans |
| title_short | Heated Corn Oil and 2,4-Decadienal Suppress Gastric Emptying and Energy Intake in Humans |
| title_sort | heated corn oil and 2 4 decadienal suppress gastric emptying and energy intake in humans |
| topic | gastric emptying rate food intake energy intake oil 2,4-decadienal appetite |
| url | https://www.mdpi.com/2072-6643/13/4/1304 |
| work_keys_str_mv | AT hideakikashima heatedcornoiland24decadienalsuppressgastricemptyingandenergyintakeinhumans AT ayumihonma heatedcornoiland24decadienalsuppressgastricemptyingandenergyintakeinhumans AT saorikamimura heatedcornoiland24decadienalsuppressgastricemptyingandenergyintakeinhumans AT sakinishimura heatedcornoiland24decadienalsuppressgastricemptyingandenergyintakeinhumans AT takashisano heatedcornoiland24decadienalsuppressgastricemptyingandenergyintakeinhumans AT shojimatsumoto heatedcornoiland24decadienalsuppressgastricemptyingandenergyintakeinhumans AT masakoyamaokaendo heatedcornoiland24decadienalsuppressgastricemptyingandenergyintakeinhumans AT yoshiyukifukuba heatedcornoiland24decadienalsuppressgastricemptyingandenergyintakeinhumans |