Effects of high-fat diet on thyroid autoimmunity in the female rat

Effects of high-fat diet on thyroid autoimmunity in the female rat

Abstract Background While contributions of dyslipidemia to autoimmune diseases have been described, its impact on thyroid autoimmunity (TA) is less clear. Programmed cell death 1(PD-1)/PD-ligand 1 (PD-L1) immune checkpoint is crucial in preventing autoimmune attack while its blockade exacerbates TA....

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Bibliographic Details
Main Authors: Zhengzheng Liao, Ying Kong, Liang Zeng, Qing Wan, Jinfang Hu, Yaojun Cai
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Endocrine Disorders
Subjects:
High-fat diet
Thyroid autoimmunity
PD-1
PD-L1
Lymphocytic infiltration
Online Access:https://doi.org/10.1186/s12902-022-01093-5

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