Assessing potential liver injury induced by Polygonum multiflorum using potential biomarkers via targeted sphingolipidomics

Assessing potential liver injury induced by Polygonum multiflorum using potential biomarkers via targeted sphingolipidomics

Context Polygonum multiflorum Thunb. (Polygonaceae) (PM) can cause potential liver injury which is typical in traditional Chinese medicines (TCMs)-induced hepatotoxicity. The mechanism involved are unclear and there are no sensitive evaluation indicators.Objective To assess PM-induced liver injury,...

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Bibliographic Details
Main Authors: Zhixin Jia, Lirong Liu, Jie Liu, Cong Fang, Mingxia Pan, Jingxuan Zhang, Yueting Li, Zhong Xian, Hongbin Xiao
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Pharmaceutical Biology
Subjects:
Ceramides
sensitive criterion
Cer (d18:1/24:1)
Cer (d18:1/26:1)
hepatotoxicity
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2022.2099908

Internet

https://www.tandfonline.com/doi/10.1080/13880209.2022.2099908

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