Control of pH in bioelectronics and applications
Ions and biomolecules are the languages that biological systems use to transfer signals in intracellular communication and organism function. As such, bioelectronic devices that conduct ions and biomolecules rather than electrons and holes are particularly suited for biological integration. Among th...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
AIP Publishing LLC
2020-12-01
|
| Series: | APL Materials |
| Online Access: | http://dx.doi.org/10.1063/5.0027464 |
| _version_ | 1818821940685570048 |
|---|---|
| author | Manping Jia Sanhita Ray Raymond Breault Marco Rolandi |
| author_facet | Manping Jia Sanhita Ray Raymond Breault Marco Rolandi |
| author_sort | Manping Jia |
| collection | DOAJ |
| description | Ions and biomolecules are the languages that biological systems use to transfer signals in intracellular communication and organism function. As such, bioelectronic devices that conduct ions and biomolecules rather than electrons and holes are particularly suited for biological integration. Among these ions, protons (H+) are important in many biochemical reactions including neuronal excitability and oxidative phosphorylation of adenosine triphosphate (ATP). In this Research Update, we describe our efforts in measuring and controlling the concentration of H+ ions in biological systems using bioelectronic devices with contacts that are made of palladium and palladium hydride (Pd/PdHx). Pd/PdHx contacts act as an electron to proton transducer and can be used in artificial membranes containing ion channels, biohybrid photodetectors, the delivery of biochemical stimuli, pH sensitive glucose sensing, and precise control of pH using machine learning. |
| first_indexed | 2024-12-18T23:16:10Z |
| format | Article |
| id | doaj.art-c5f5588cd99c4675a61e97c413274664 |
| institution | Directory Open Access Journal |
| issn | 2166-532X |
| language | English |
| last_indexed | 2024-12-18T23:16:10Z |
| publishDate | 2020-12-01 |
| publisher | AIP Publishing LLC |
| record_format | Article |
| series | APL Materials |
| spelling | doaj.art-c5f5588cd99c4675a61e97c4132746642022-12-21T20:48:10ZengAIP Publishing LLCAPL Materials2166-532X2020-12-01812120704120704-810.1063/5.0027464Control of pH in bioelectronics and applicationsManping Jia0Sanhita Ray1Raymond Breault2Marco Rolandi3Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, California 95064, USADepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, California 95064, USADepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, California 95064, USADepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, California 95064, USAIons and biomolecules are the languages that biological systems use to transfer signals in intracellular communication and organism function. As such, bioelectronic devices that conduct ions and biomolecules rather than electrons and holes are particularly suited for biological integration. Among these ions, protons (H+) are important in many biochemical reactions including neuronal excitability and oxidative phosphorylation of adenosine triphosphate (ATP). In this Research Update, we describe our efforts in measuring and controlling the concentration of H+ ions in biological systems using bioelectronic devices with contacts that are made of palladium and palladium hydride (Pd/PdHx). Pd/PdHx contacts act as an electron to proton transducer and can be used in artificial membranes containing ion channels, biohybrid photodetectors, the delivery of biochemical stimuli, pH sensitive glucose sensing, and precise control of pH using machine learning.http://dx.doi.org/10.1063/5.0027464 |
| spellingShingle | Manping Jia Sanhita Ray Raymond Breault Marco Rolandi Control of pH in bioelectronics and applications APL Materials |
| title | Control of pH in bioelectronics and applications |
| title_full | Control of pH in bioelectronics and applications |
| title_fullStr | Control of pH in bioelectronics and applications |
| title_full_unstemmed | Control of pH in bioelectronics and applications |
| title_short | Control of pH in bioelectronics and applications |
| title_sort | control of ph in bioelectronics and applications |
| url | http://dx.doi.org/10.1063/5.0027464 |
| work_keys_str_mv | AT manpingjia controlofphinbioelectronicsandapplications AT sanhitaray controlofphinbioelectronicsandapplications AT raymondbreault controlofphinbioelectronicsandapplications AT marcorolandi controlofphinbioelectronicsandapplications |