Correlation of Serum and Salivary Biochemical Parameters in end Stage Renal Disease Patients Undergoing Hemodialysis in Pre and Post-Dialysis State
Aim: The aim of this study is to compare the salivary urea, creatine, sodium, potassium and phosphate in pre dialysis and post dialysis state in end stage renal disease patients and compare with the serum counterpart. Materials and Methods: The study group was selected from patients undergoing...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2014-12-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/5306/10404_CE(Ra)_F(Sh)_PF1(PAK)_PFA(Sh)_PF2(PAG).pdf |
| _version_ | 1819228353009287168 |
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| author | C. Seethalakshmi D. Koteeswaran V. Chiranjeevi |
| author_facet | C. Seethalakshmi D. Koteeswaran V. Chiranjeevi |
| author_sort | C. Seethalakshmi |
| collection | DOAJ |
| description | Aim: The aim of this study is to compare the salivary urea,
creatine, sodium, potassium and phosphate in pre dialysis
and post dialysis state in end stage renal disease patients and
compare with the serum counterpart.
Materials and Methods: The study group was selected from
patients undergoing hemodialysis due renal failure of any cause,
who are undergoing dialysis for at least one year duration in a
private hospital in Chennai. The total number of subjects was
30. The venous blood was collected from the study group
just prior to the dialysis and after the dialysis from the venous
catheter which is placed for the purpose of hemodialysis. The
collected samples were immediately (within 15 min) submitted
to the laboratory for the biochemical examination of urea,
creatinine, sodium, potassium and phosphate by an automated
biochemical analyser. Unstimulated whole saliva was collected
by spitting method from study group both before and after
dialysis. The collected samples were immediately submitted
to the laboratory for the biochemical examination of urea,
creatinine, sodium, potassium and phosphate by an automated
biochemical analyser.
Result: The paired t-test analysis was done in pre and post
blood urea, creatinine, potassium and phosphate which was
significant with a p-value of < 0.0001 and the same analysis was
done in salivary urea in pre and post-dialysis state which also
gave a significant reduction in the parameters with a p-value of
< 0.0001. |
| first_indexed | 2024-12-23T10:55:55Z |
| format | Article |
| id | doaj.art-c5f80eb854f1427591dc62cfa93f5f10 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-23T10:55:55Z |
| publishDate | 2014-12-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-c5f80eb854f1427591dc62cfa93f5f102022-12-21T17:49:47ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-12-01812CC12CC1410.7860/JCDR/2014/10404.5306Correlation of Serum and Salivary Biochemical Parameters in end Stage Renal Disease Patients Undergoing Hemodialysis in Pre and Post-Dialysis StateC. Seethalakshmi0D. Koteeswaran1V. Chiranjeevi2Lecturer, Department of Oral Medicine and Radiology, Chettinad Dental College and Research Institute, Chennai, India.Professor, Department of Oral Medicine and Radiology, Meenakshi Ammal Dental College, Chennai, India.Professor and Head, Department of Nephrology, Meenakshi Medical College, Chennai, India.Aim: The aim of this study is to compare the salivary urea, creatine, sodium, potassium and phosphate in pre dialysis and post dialysis state in end stage renal disease patients and compare with the serum counterpart. Materials and Methods: The study group was selected from patients undergoing hemodialysis due renal failure of any cause, who are undergoing dialysis for at least one year duration in a private hospital in Chennai. The total number of subjects was 30. The venous blood was collected from the study group just prior to the dialysis and after the dialysis from the venous catheter which is placed for the purpose of hemodialysis. The collected samples were immediately (within 15 min) submitted to the laboratory for the biochemical examination of urea, creatinine, sodium, potassium and phosphate by an automated biochemical analyser. Unstimulated whole saliva was collected by spitting method from study group both before and after dialysis. The collected samples were immediately submitted to the laboratory for the biochemical examination of urea, creatinine, sodium, potassium and phosphate by an automated biochemical analyser. Result: The paired t-test analysis was done in pre and post blood urea, creatinine, potassium and phosphate which was significant with a p-value of < 0.0001 and the same analysis was done in salivary urea in pre and post-dialysis state which also gave a significant reduction in the parameters with a p-value of < 0.0001.https://jcdr.net/articles/PDF/5306/10404_CE(Ra)_F(Sh)_PF1(PAK)_PFA(Sh)_PF2(PAG).pdfbiochemical analysisend stage renal diseasekidney diseasesalivary diagnostics |
| spellingShingle | C. Seethalakshmi D. Koteeswaran V. Chiranjeevi Correlation of Serum and Salivary Biochemical Parameters in end Stage Renal Disease Patients Undergoing Hemodialysis in Pre and Post-Dialysis State Journal of Clinical and Diagnostic Research biochemical analysis end stage renal disease kidney disease salivary diagnostics |
| title | Correlation of Serum and Salivary Biochemical Parameters in end Stage Renal Disease Patients Undergoing Hemodialysis in Pre and Post-Dialysis State |
| title_full | Correlation of Serum and Salivary Biochemical Parameters in end Stage Renal Disease Patients Undergoing Hemodialysis in Pre and Post-Dialysis State |
| title_fullStr | Correlation of Serum and Salivary Biochemical Parameters in end Stage Renal Disease Patients Undergoing Hemodialysis in Pre and Post-Dialysis State |
| title_full_unstemmed | Correlation of Serum and Salivary Biochemical Parameters in end Stage Renal Disease Patients Undergoing Hemodialysis in Pre and Post-Dialysis State |
| title_short | Correlation of Serum and Salivary Biochemical Parameters in end Stage Renal Disease Patients Undergoing Hemodialysis in Pre and Post-Dialysis State |
| title_sort | correlation of serum and salivary biochemical parameters in end stage renal disease patients undergoing hemodialysis in pre and post dialysis state |
| topic | biochemical analysis end stage renal disease kidney disease salivary diagnostics |
| url | https://jcdr.net/articles/PDF/5306/10404_CE(Ra)_F(Sh)_PF1(PAK)_PFA(Sh)_PF2(PAG).pdf |
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