New approach to heart rate variability analysis based on cardiophysiological biomarkers
Background: The heart rate variability (HRV) analysis is a well-known method demonstrating its value over the years in different medical fields. However, it still has its known limitations. Material and methods: The new approach to HRV analysis is based on a complementary HRV standard analysis with...
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| Format: | Article |
| Language: | English |
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Scientific Medical Association of Moldova
2018-10-01
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| Series: | The Moldovan Medical Journal |
| Subjects: | |
| Online Access: | http://moldmedjournal.md/wp-content/uploads/2018/11/moldmedjournal-2018-61-3-sidorenko-et-al-full-article.pdf |
| _version_ | 1819181635063513088 |
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| author | Ludmila Sidorenko Ivan Diaz-Ramirez Victor Vovc Gert Baumann |
| author_facet | Ludmila Sidorenko Ivan Diaz-Ramirez Victor Vovc Gert Baumann |
| author_sort | Ludmila Sidorenko |
| collection | DOAJ |
| description | Background: The heart rate variability (HRV) analysis is a well-known method demonstrating its value over the years in different medical fields. However, it still has its known limitations. Material and methods: The new approach to HRV analysis is based on a complementary HRV standard analysis with new cardiophysiological biomarkers. The biomarkers are assessed on cardiorhythmograms obtained by a 5-minute ECG recording using a specialized hardware (Polyspectrum-HRV-device, Neurosoft). Results: A possible applicative value of the biomarkers is shown on examples of how a prognosis for recurrence of atrial fibrillation (AFib) could be made. When in a rest-state cardiorhythmogram are observed LF drops and are followed by a pathological counterregulation, prognostically, recurrence of atrial fibrillation is expected. When in a cardiorhythmogram LF drops are observed and are followed by a physiological counterregulation, prognostically, sinus rhythm is expected. Physiological background of the biomarkers: increased central modulation of the heart in rest state of a patient, a sympathetic overflow of the heart in calm state and insufficiency of compensatory parasymphatetic counteractivation. Limitations of the paper: this is a methodological paper without description of patients. This paper will be followed by a clinical paper in which we are going to describe the validation of these cardiophysiological biomarkers on patients with AFib. Conclusions: Complementary to the standard HRV analysis, cardiophysiological biomarkers should be assessed: LF drops and HF counterregulation could be used for prognosis construction in cardiology. |
| first_indexed | 2024-12-22T22:33:22Z |
| format | Article |
| id | doaj.art-c5f899622e8344b69fab820275839145 |
| institution | Directory Open Access Journal |
| issn | 2537-6373 2537-6381 |
| language | English |
| last_indexed | 2024-12-22T22:33:22Z |
| publishDate | 2018-10-01 |
| publisher | Scientific Medical Association of Moldova |
| record_format | Article |
| series | The Moldovan Medical Journal |
| spelling | doaj.art-c5f899622e8344b69fab8202758391452022-12-21T18:10:22ZengScientific Medical Association of MoldovaThe Moldovan Medical Journal2537-63732537-63812018-10-01613394610.5281/zenodo.1465926New approach to heart rate variability analysis based on cardiophysiological biomarkersLudmila Sidorenko0Ivan Diaz-Ramirez1Victor Vovc2Gert Baumann3Department of Physiology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of MoldovaDepartment of Cardiology and Angiology, Charité University Clinic, Berlin, GermanyDepartment of Physiology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of MoldovaDepartment of Cardiology and Angiology, Charité University Clinic, Berlin, GermanyBackground: The heart rate variability (HRV) analysis is a well-known method demonstrating its value over the years in different medical fields. However, it still has its known limitations. Material and methods: The new approach to HRV analysis is based on a complementary HRV standard analysis with new cardiophysiological biomarkers. The biomarkers are assessed on cardiorhythmograms obtained by a 5-minute ECG recording using a specialized hardware (Polyspectrum-HRV-device, Neurosoft). Results: A possible applicative value of the biomarkers is shown on examples of how a prognosis for recurrence of atrial fibrillation (AFib) could be made. When in a rest-state cardiorhythmogram are observed LF drops and are followed by a pathological counterregulation, prognostically, recurrence of atrial fibrillation is expected. When in a cardiorhythmogram LF drops are observed and are followed by a physiological counterregulation, prognostically, sinus rhythm is expected. Physiological background of the biomarkers: increased central modulation of the heart in rest state of a patient, a sympathetic overflow of the heart in calm state and insufficiency of compensatory parasymphatetic counteractivation. Limitations of the paper: this is a methodological paper without description of patients. This paper will be followed by a clinical paper in which we are going to describe the validation of these cardiophysiological biomarkers on patients with AFib. Conclusions: Complementary to the standard HRV analysis, cardiophysiological biomarkers should be assessed: LF drops and HF counterregulation could be used for prognosis construction in cardiology.http://moldmedjournal.md/wp-content/uploads/2018/11/moldmedjournal-2018-61-3-sidorenko-et-al-full-article.pdfcardiophysiological biomarkersheart rate variability |
| spellingShingle | Ludmila Sidorenko Ivan Diaz-Ramirez Victor Vovc Gert Baumann New approach to heart rate variability analysis based on cardiophysiological biomarkers The Moldovan Medical Journal cardiophysiological biomarkers heart rate variability |
| title | New approach to heart rate variability analysis based on cardiophysiological biomarkers |
| title_full | New approach to heart rate variability analysis based on cardiophysiological biomarkers |
| title_fullStr | New approach to heart rate variability analysis based on cardiophysiological biomarkers |
| title_full_unstemmed | New approach to heart rate variability analysis based on cardiophysiological biomarkers |
| title_short | New approach to heart rate variability analysis based on cardiophysiological biomarkers |
| title_sort | new approach to heart rate variability analysis based on cardiophysiological biomarkers |
| topic | cardiophysiological biomarkers heart rate variability |
| url | http://moldmedjournal.md/wp-content/uploads/2018/11/moldmedjournal-2018-61-3-sidorenko-et-al-full-article.pdf |
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