Analysis of Cross-Association between mRNA Expression and RNAi Efficacy for Predictive Target Discovery in Colon Cancers

Analysis of Cross-Association between mRNA Expression and RNAi Efficacy for Predictive Target Discovery in Colon Cancers

The availability of large-scale, collateral mRNA expression and RNAi data from diverse cancer cell types provides useful resources for the discovery of anticancer targets for which inhibitory efficacy can be predicted from gene expression. Here, we calculated bidirectional cross-association scores (...

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Bibliographic Details
Main Authors: Euna Jeong, Yejin Lee, Youngju Kim, Jieun Lee, Sukjoon Yoon
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
gene expression
shRNA screening
CRISPR
anticancer targets
biomarkers
precision medicine
Online Access:https://www.mdpi.com/2072-6694/12/11/3091

Internet

https://www.mdpi.com/2072-6694/12/11/3091

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