Searching for solutions to the missing heritability problem

Rare genetic variants in yeast explain a large amount of phenotypic variation in a complex trait like growth.

Bibliographic Details
Main Author: Luisa F Pallares
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/53018
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author Luisa F Pallares
author_facet Luisa F Pallares
author_sort Luisa F Pallares
collection DOAJ
description Rare genetic variants in yeast explain a large amount of phenotypic variation in a complex trait like growth.
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spelling doaj.art-c5fbebefeefd4864bc6a061889f74c862022-12-22T04:32:15ZengeLife Sciences Publications LtdeLife2050-084X2019-12-01810.7554/eLife.53018Searching for solutions to the missing heritability problemLuisa F Pallares0https://orcid.org/0000-0001-6547-1901Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, United States; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, United StatesRare genetic variants in yeast explain a large amount of phenotypic variation in a complex trait like growth.https://elifesciences.org/articles/53018genetic architectureGWASlow-frequency variantscomplex traitsrare variantsQTL
spellingShingle Luisa F Pallares
Searching for solutions to the missing heritability problem
eLife
genetic architecture
GWAS
low-frequency variants
complex traits
rare variants
QTL
title Searching for solutions to the missing heritability problem
title_full Searching for solutions to the missing heritability problem
title_fullStr Searching for solutions to the missing heritability problem
title_full_unstemmed Searching for solutions to the missing heritability problem
title_short Searching for solutions to the missing heritability problem
title_sort searching for solutions to the missing heritability problem
topic genetic architecture
GWAS
low-frequency variants
complex traits
rare variants
QTL
url https://elifesciences.org/articles/53018
work_keys_str_mv AT luisafpallares searchingforsolutionstothemissingheritabilityproblem