Caution Advised Using Combination Ketoconazole and PD-1 Inhibitors

Caution Advised Using Combination Ketoconazole and PD-1 Inhibitors

ABSTRACT: Objective: Immune checkpoint inhibitors are approved to treat multiple cancers. We report life-threatening hepatic failure in 2 consecutive patients with Cushing syndrome that were treated with ketoconazole (KTZ) in combination with 2 different programmed cell death protein 1 (PD-1) inhib...

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Bibliographic Details
Main Authors: Yingying Yang, Joel R. Hecht, Sandy Ting Liu, Melissa J. Cohen, Steven D. Hart, Hanlin L. Wang, Anthony P. Heaney
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:AACE Clinical Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2376060520306179

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