Analysis of Specific Allergens in the Serum of Patients with Allergic Diseases in the Shanxi Region of China
The aim of this study is to analyze the distribution characteristics of specific allergens based on the immunoglobulin E (IgE) test, performed using the sera of patients with allergic diseases in the Shanxi region of China. Sera from 3141 patients with allergic diseases were analyzed with immunoblot...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Hindawi-Wiley
2023-01-01
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| Series: | Cellular Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2023/1460961 |
| _version_ | 1826993252361830400 |
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| author | Jing Wu Yuee Liu Min Xie Yanzhi Cui Yaona Wei Yan Cheng Jing Yang Hongxia Zhang Lei Wang |
| author_facet | Jing Wu Yuee Liu Min Xie Yanzhi Cui Yaona Wei Yan Cheng Jing Yang Hongxia Zhang Lei Wang |
| author_sort | Jing Wu |
| collection | DOAJ |
| description | The aim of this study is to analyze the distribution characteristics of specific allergens based on the immunoglobulin E (IgE) test, performed using the sera of patients with allergic diseases in the Shanxi region of China. Sera from 3141 patients with allergic diseases were analyzed with immunoblotting for IgE antibodies specific to inhaled and ingested allergens. The distribution of allergens and association with factors such as disease profile, sex, age, and cosensitization of the patients who tested positive were analyzed. The most common positive rate of IgE specific to inhaled allergens was mugwort, followed by dust mite mix and common ragweed. The most common positive rate of IgE specific to ingested allergens was crab, followed by egg white and sea fish mix. When analyzed according to disease profile, mugwort was the most common allergen in asthma, rhinitis, and asthma combined with rhinitis. When analyzed by season, the allergens with the highest positive rates included tree mix (willow/poplar/elm), common ragweed, mugwort, and hop pollen from July through September. When analyzed by age, the allergens with the highest positive rates were tree mix, common ragweed, hop, house dust, cow’s milk, mutton/lamb, and peanut in participants aged 0–18 years and egg white in those aged ≥60 years. The radar charts showed cosensitization to multiple allergens. In the Shanxi region, the primary inhaled allergens were mugwort, dust mite mix (1: house dust mite/dust mite), and common ragweed. The primary ingested allergens were crab, egg white, and sea fish mix. There were differences in the positive rates of the allergens between genders, age groups, and seasons, and multiple allergens can cosensitize patients. |
| first_indexed | 2024-04-09T13:15:59Z |
| format | Article |
| id | doaj.art-c605b2ad9575444297109b0221842878 |
| institution | Directory Open Access Journal |
| issn | 1462-5822 |
| language | English |
| last_indexed | 2025-02-18T09:01:10Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi-Wiley |
| record_format | Article |
| series | Cellular Microbiology |
| spelling | doaj.art-c605b2ad9575444297109b02218428782024-11-02T23:52:53ZengHindawi-WileyCellular Microbiology1462-58222023-01-01202310.1155/2023/1460961Analysis of Specific Allergens in the Serum of Patients with Allergic Diseases in the Shanxi Region of ChinaJing Wu0Yuee Liu1Min Xie2Yanzhi Cui3Yaona Wei4Yan Cheng5Jing Yang6Hongxia Zhang7Lei Wang8Department of Respiratory MedicineDepartment of Respiratory MedicineDepartment of Respiratory MedicineDepartment of Respiratory MedicineDepartment of Respiratory MedicineDepartment of Respiratory MedicineDepartment of Respiratory MedicineDepartment of Respiratory MedicineDepartment of Respiratory MedicineThe aim of this study is to analyze the distribution characteristics of specific allergens based on the immunoglobulin E (IgE) test, performed using the sera of patients with allergic diseases in the Shanxi region of China. Sera from 3141 patients with allergic diseases were analyzed with immunoblotting for IgE antibodies specific to inhaled and ingested allergens. The distribution of allergens and association with factors such as disease profile, sex, age, and cosensitization of the patients who tested positive were analyzed. The most common positive rate of IgE specific to inhaled allergens was mugwort, followed by dust mite mix and common ragweed. The most common positive rate of IgE specific to ingested allergens was crab, followed by egg white and sea fish mix. When analyzed according to disease profile, mugwort was the most common allergen in asthma, rhinitis, and asthma combined with rhinitis. When analyzed by season, the allergens with the highest positive rates included tree mix (willow/poplar/elm), common ragweed, mugwort, and hop pollen from July through September. When analyzed by age, the allergens with the highest positive rates were tree mix, common ragweed, hop, house dust, cow’s milk, mutton/lamb, and peanut in participants aged 0–18 years and egg white in those aged ≥60 years. The radar charts showed cosensitization to multiple allergens. In the Shanxi region, the primary inhaled allergens were mugwort, dust mite mix (1: house dust mite/dust mite), and common ragweed. The primary ingested allergens were crab, egg white, and sea fish mix. There were differences in the positive rates of the allergens between genders, age groups, and seasons, and multiple allergens can cosensitize patients.http://dx.doi.org/10.1155/2023/1460961 |
| spellingShingle | Jing Wu Yuee Liu Min Xie Yanzhi Cui Yaona Wei Yan Cheng Jing Yang Hongxia Zhang Lei Wang Analysis of Specific Allergens in the Serum of Patients with Allergic Diseases in the Shanxi Region of China Cellular Microbiology |
| title | Analysis of Specific Allergens in the Serum of Patients with Allergic Diseases in the Shanxi Region of China |
| title_full | Analysis of Specific Allergens in the Serum of Patients with Allergic Diseases in the Shanxi Region of China |
| title_fullStr | Analysis of Specific Allergens in the Serum of Patients with Allergic Diseases in the Shanxi Region of China |
| title_full_unstemmed | Analysis of Specific Allergens in the Serum of Patients with Allergic Diseases in the Shanxi Region of China |
| title_short | Analysis of Specific Allergens in the Serum of Patients with Allergic Diseases in the Shanxi Region of China |
| title_sort | analysis of specific allergens in the serum of patients with allergic diseases in the shanxi region of china |
| url | http://dx.doi.org/10.1155/2023/1460961 |
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