Clinical observation of ondansetron administration at different time in preventing nausea and vomiting after pediatric strabismus surgery
AIM: To observe the efficacy of ondansetron by intravenous injection at different time in preventing nausea and vomiting after pediatric strabismus surgery. <p>METHODS: Totally 90 children aged 3-11y were randomly selected for pediatric strabismus surgery from June 2013 to August 2013 in our h...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2014-06-01
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| Series: | Guoji Yanke Zazhi |
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| Online Access: | http://www.ies.net.cn/cn_publish/2014/6/201406058.pdf |
| _version_ | 1819206455242260480 |
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| author | Huai-Gang Liu Xiao-Jing Li Jian-Jun Li |
| author_facet | Huai-Gang Liu Xiao-Jing Li Jian-Jun Li |
| author_sort | Huai-Gang Liu |
| collection | DOAJ |
| description | AIM: To observe the efficacy of ondansetron by intravenous injection at different time in preventing nausea and vomiting after pediatric strabismus surgery. <p>METHODS: Totally 90 children aged 3-11y were randomly selected for pediatric strabismus surgery from June 2013 to August 2013 in our hospital. The ASA grade of all children were Ⅰ-Ⅱ. Children were randomly divided into three groups with 30 cases each. Group A received intravenous drip of ondansetron 0.1mg/kg before surgery. Group B received intravenous drip of ondansetron 0.1mg/kg after surgery. Group C as control group was not given ondansetron. The number and severity of nausea and vomiting were observed within 24h after surgery. <p>RESULTS: There were no statistical significance in patients' gender, weight, age, duration of anesthesia, ketamine dosage and vital signs intraoperative between the three groups(<i>P</i>>0.05). The incidence rate of postoperative nausea and vomiting(PONV)of group A and B were significantly lower than group C(<i>P</i><0.05). The incidence rate of PONV of group A and group B have no significant difference(<i>P</i>>0.05). <p>CONCLUSION: Using ondansetron is effective and safe in preventing PONV before and at the end of the pediatric strabismus surgery, which can also improve safety and be lower cost. It is a worthy promoting antiemetic approach for eye surgery. |
| first_indexed | 2024-12-23T05:07:52Z |
| format | Article |
| id | doaj.art-c6063919f2b140849724d867d22726c5 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-23T05:07:52Z |
| publishDate | 2014-06-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-c6063919f2b140849724d867d22726c52022-12-21T17:59:01ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232014-06-011461177117810.3980/j.issn.1672-5123.2014.06.58Clinical observation of ondansetron administration at different time in preventing nausea and vomiting after pediatric strabismus surgeryHuai-Gang Liu0Xiao-Jing Li1Jian-Jun Li2Jinan Mingshui Eye Hospital, Jinan 250200, Shandong Province, ChinaJinan Mingshui Eye Hospital, Jinan 250200, Shandong Province, ChinaDepartment of Anesthesiology, Qilu Hospital of Shandong University, Jinan 250012, Shandong Province,ChinaAIM: To observe the efficacy of ondansetron by intravenous injection at different time in preventing nausea and vomiting after pediatric strabismus surgery. <p>METHODS: Totally 90 children aged 3-11y were randomly selected for pediatric strabismus surgery from June 2013 to August 2013 in our hospital. The ASA grade of all children were Ⅰ-Ⅱ. Children were randomly divided into three groups with 30 cases each. Group A received intravenous drip of ondansetron 0.1mg/kg before surgery. Group B received intravenous drip of ondansetron 0.1mg/kg after surgery. Group C as control group was not given ondansetron. The number and severity of nausea and vomiting were observed within 24h after surgery. <p>RESULTS: There were no statistical significance in patients' gender, weight, age, duration of anesthesia, ketamine dosage and vital signs intraoperative between the three groups(<i>P</i>>0.05). The incidence rate of postoperative nausea and vomiting(PONV)of group A and B were significantly lower than group C(<i>P</i><0.05). The incidence rate of PONV of group A and group B have no significant difference(<i>P</i>>0.05). <p>CONCLUSION: Using ondansetron is effective and safe in preventing PONV before and at the end of the pediatric strabismus surgery, which can also improve safety and be lower cost. It is a worthy promoting antiemetic approach for eye surgery.http://www.ies.net.cn/cn_publish/2014/6/201406058.pdfondansetronpediatric strabismus surgerynausea and vomitingnausea and vomiting |
| spellingShingle | Huai-Gang Liu Xiao-Jing Li Jian-Jun Li Clinical observation of ondansetron administration at different time in preventing nausea and vomiting after pediatric strabismus surgery Guoji Yanke Zazhi ondansetron pediatric strabismus surgery nausea and vomiting nausea and vomiting |
| title | Clinical observation of ondansetron administration at different time in preventing nausea and vomiting after pediatric strabismus surgery |
| title_full | Clinical observation of ondansetron administration at different time in preventing nausea and vomiting after pediatric strabismus surgery |
| title_fullStr | Clinical observation of ondansetron administration at different time in preventing nausea and vomiting after pediatric strabismus surgery |
| title_full_unstemmed | Clinical observation of ondansetron administration at different time in preventing nausea and vomiting after pediatric strabismus surgery |
| title_short | Clinical observation of ondansetron administration at different time in preventing nausea and vomiting after pediatric strabismus surgery |
| title_sort | clinical observation of ondansetron administration at different time in preventing nausea and vomiting after pediatric strabismus surgery |
| topic | ondansetron pediatric strabismus surgery nausea and vomiting nausea and vomiting |
| url | http://www.ies.net.cn/cn_publish/2014/6/201406058.pdf |
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