PolysacDB: a database of microbial polysaccharide antigens and their antibodies.
Vaccines based on microbial cell surface polysaccharides have long been considered as attractive means to control infectious diseases. To realize this goal, detailed systematic information about the antigenic polysaccharide is necessary. However, only a few databases that provide limited knowledge i...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3324500?pdf=render |
| _version_ | 1819035105804419072 |
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| author | Abhijit Aithal Arun Sharma Shilpy Joshi Gajendra P S Raghava Grish C Varshney |
| author_facet | Abhijit Aithal Arun Sharma Shilpy Joshi Gajendra P S Raghava Grish C Varshney |
| author_sort | Abhijit Aithal |
| collection | DOAJ |
| description | Vaccines based on microbial cell surface polysaccharides have long been considered as attractive means to control infectious diseases. To realize this goal, detailed systematic information about the antigenic polysaccharide is necessary. However, only a few databases that provide limited knowledge in this area are available. This paper describes PolysacDB, a manually curated database of antigenic polysaccharides. We collected and compiled comprehensive information from literature and web resources about antigenic polysaccharides of microbial origin. The current version of the database has 1,554 entries of 149 different antigenic polysaccharides from 347 different microbes. Each entry provides comprehensive information about an antigenic polysaccharide, i.e., its origin, function, protocols for its conjugation to carriers, antibodies produced, details of assay systems, specificities of antibodies, proposed epitopes involved and antibody utilities. For convenience to the user, we have integrated web interface for searching, advanced searching and browsing data in database. This database will be useful for researchers working on polysaccharide-based vaccines. It is freely available from the URL: http://crdd.osdd.net/raghava/polysacdb/. |
| first_indexed | 2024-12-21T07:44:21Z |
| format | Article |
| id | doaj.art-c60b26fe055746b09c6e80512aaa34e9 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-21T07:44:21Z |
| publishDate | 2012-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-c60b26fe055746b09c6e80512aaa34e92022-12-21T19:11:14ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-0174e3461310.1371/journal.pone.0034613PolysacDB: a database of microbial polysaccharide antigens and their antibodies.Abhijit AithalArun SharmaShilpy JoshiGajendra P S RaghavaGrish C VarshneyVaccines based on microbial cell surface polysaccharides have long been considered as attractive means to control infectious diseases. To realize this goal, detailed systematic information about the antigenic polysaccharide is necessary. However, only a few databases that provide limited knowledge in this area are available. This paper describes PolysacDB, a manually curated database of antigenic polysaccharides. We collected and compiled comprehensive information from literature and web resources about antigenic polysaccharides of microbial origin. The current version of the database has 1,554 entries of 149 different antigenic polysaccharides from 347 different microbes. Each entry provides comprehensive information about an antigenic polysaccharide, i.e., its origin, function, protocols for its conjugation to carriers, antibodies produced, details of assay systems, specificities of antibodies, proposed epitopes involved and antibody utilities. For convenience to the user, we have integrated web interface for searching, advanced searching and browsing data in database. This database will be useful for researchers working on polysaccharide-based vaccines. It is freely available from the URL: http://crdd.osdd.net/raghava/polysacdb/.http://europepmc.org/articles/PMC3324500?pdf=render |
| spellingShingle | Abhijit Aithal Arun Sharma Shilpy Joshi Gajendra P S Raghava Grish C Varshney PolysacDB: a database of microbial polysaccharide antigens and their antibodies. PLoS ONE |
| title | PolysacDB: a database of microbial polysaccharide antigens and their antibodies. |
| title_full | PolysacDB: a database of microbial polysaccharide antigens and their antibodies. |
| title_fullStr | PolysacDB: a database of microbial polysaccharide antigens and their antibodies. |
| title_full_unstemmed | PolysacDB: a database of microbial polysaccharide antigens and their antibodies. |
| title_short | PolysacDB: a database of microbial polysaccharide antigens and their antibodies. |
| title_sort | polysacdb a database of microbial polysaccharide antigens and their antibodies |
| url | http://europepmc.org/articles/PMC3324500?pdf=render |
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