P2 DETERMINATION OF LOCAL PULSE WAVE VELOCITY DOES NOT AFFECTED BY REFLECTION

Objective: PWV is an important indicator of arterial stiffness and cardiovascular diseases. Local PWV would provide a more accurate estimation of local stiffness than does regional PWV. Local PWV is commonly determined by loop techniques, such as the PU-loop method and the aim of this study is to ex...

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Main Authors: Ye Li, Ashraf Khir
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125930016/view
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author Ye Li
Ashraf Khir
author_facet Ye Li
Ashraf Khir
author_sort Ye Li
collection DOAJ
description Objective: PWV is an important indicator of arterial stiffness and cardiovascular diseases. Local PWV would provide a more accurate estimation of local stiffness than does regional PWV. Local PWV is commonly determined by loop techniques, such as the PU-loop method and the aim of this study is to examine the effect of reflections on the accuracy of determining local PWV by loop Methods. Methods: Pressure and flow were measured along a flexible tube that was connected to three positive and three negative reflections. PWV was calculated using the PU-loop method and wave intensity analysis was used to separate the pressure and flow velocity waveforms, using PWV of 20.2 m/s measured determined by the foot-to-foot method. Local reflection coefficient I was calculated as the ratio of magnitudes of backward to forward pressure. Results: Figure 1 shows local PWV is not affected by the reflection until measurements were taken at 80 cm away from reflection site, when it starts to increase or decrease depending on the type of the reflection. The threshold of R corresponding to the non-affected PWV by reflections is ±0.36 ± 0.05 (mean ± SD). Conclusions: The results of this study indicate that local PWV determined by PU-loop are only affected by reflections when the local reflection coefficient is greater than ±0.36 ± 0.05, irrespective of the distance to the reflection site. If/given reflections of the current study are comparable to those measured in vivo, PWV would not be affected by reflections in the arterial system.
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spelling doaj.art-c60b52f5aae642b0bba1260a113e5a632022-12-22T00:33:50ZengBMCArtery Research1876-44012018-12-012410.1016/j.artres.2018.10.055P2 DETERMINATION OF LOCAL PULSE WAVE VELOCITY DOES NOT AFFECTED BY REFLECTIONYe LiAshraf KhirObjective: PWV is an important indicator of arterial stiffness and cardiovascular diseases. Local PWV would provide a more accurate estimation of local stiffness than does regional PWV. Local PWV is commonly determined by loop techniques, such as the PU-loop method and the aim of this study is to examine the effect of reflections on the accuracy of determining local PWV by loop Methods. Methods: Pressure and flow were measured along a flexible tube that was connected to three positive and three negative reflections. PWV was calculated using the PU-loop method and wave intensity analysis was used to separate the pressure and flow velocity waveforms, using PWV of 20.2 m/s measured determined by the foot-to-foot method. Local reflection coefficient I was calculated as the ratio of magnitudes of backward to forward pressure. Results: Figure 1 shows local PWV is not affected by the reflection until measurements were taken at 80 cm away from reflection site, when it starts to increase or decrease depending on the type of the reflection. The threshold of R corresponding to the non-affected PWV by reflections is ±0.36 ± 0.05 (mean ± SD). Conclusions: The results of this study indicate that local PWV determined by PU-loop are only affected by reflections when the local reflection coefficient is greater than ±0.36 ± 0.05, irrespective of the distance to the reflection site. If/given reflections of the current study are comparable to those measured in vivo, PWV would not be affected by reflections in the arterial system.https://www.atlantis-press.com/article/125930016/view
spellingShingle Ye Li
Ashraf Khir
P2 DETERMINATION OF LOCAL PULSE WAVE VELOCITY DOES NOT AFFECTED BY REFLECTION
Artery Research
title P2 DETERMINATION OF LOCAL PULSE WAVE VELOCITY DOES NOT AFFECTED BY REFLECTION
title_full P2 DETERMINATION OF LOCAL PULSE WAVE VELOCITY DOES NOT AFFECTED BY REFLECTION
title_fullStr P2 DETERMINATION OF LOCAL PULSE WAVE VELOCITY DOES NOT AFFECTED BY REFLECTION
title_full_unstemmed P2 DETERMINATION OF LOCAL PULSE WAVE VELOCITY DOES NOT AFFECTED BY REFLECTION
title_short P2 DETERMINATION OF LOCAL PULSE WAVE VELOCITY DOES NOT AFFECTED BY REFLECTION
title_sort p2 determination of local pulse wave velocity does not affected by reflection
url https://www.atlantis-press.com/article/125930016/view
work_keys_str_mv AT yeli p2determinationoflocalpulsewavevelocitydoesnotaffectedbyreflection
AT ashrafkhir p2determinationoflocalpulsewavevelocitydoesnotaffectedbyreflection