Enhancement of Bottle Gourd Oil Activity via Optimized Self-Dispersing Lipid Formulations (SDLFs) to Mitigate Isoproterenol-Evoked Cardiac Toxicity in Rats via Modulating BNP, MMP2, and miRNA-21 and miRNA-23a Genes’ Expression

Enhancement of Bottle Gourd Oil Activity via Optimized Self-Dispersing Lipid Formulations (SDLFs) to Mitigate Isoproterenol-Evoked Cardiac Toxicity in Rats via Modulating BNP, MMP2, and miRNA-21 and miRNA-23a Genes’ Expression

Bottle gourd (BG) oil (family Cucurbitaceae) has several pharmacological activities including a reduction of the hazard of cardiovascular and atherosclerosis conditions. This work aimed to develop and optimize self-dispersing lipid formulations (SDLFs) of BG oil by applying a full 3<sup>2</...

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Bibliographic Details
Main Authors: Shereen S. El-Mancy, Sylvia A. Boshra, Osama S. Elnahas, Sahar M. Fayez, Nermin M. Sheta
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
bottle gourd oil
self-dispersing lipid formulations
BNP
MMP2
miRNAs
Online Access:https://www.mdpi.com/1420-3049/28/16/6168

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