Diabetic Kidney Disease versus Primary Glomerular Disease: A Propensity Score-Matched Analysis of Association between Ambulatory Blood-Pressure Monitoring and Target-Organ Damage
Diabetic kidney disease (DKD) and primary glomerular disease (PGD) are the main causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD). This study was conducted to compare the characteristics of ambulatory blood-pressure monitoring (ABPM) and its relationship with target-organ dam...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/1/167 |
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| author | Tiantian Yu Shicong Song Xiaoqiu Chen Tanqi Lou Jun Zhang Hui Peng Man Li Cheng Wang |
| author_facet | Tiantian Yu Shicong Song Xiaoqiu Chen Tanqi Lou Jun Zhang Hui Peng Man Li Cheng Wang |
| author_sort | Tiantian Yu |
| collection | DOAJ |
| description | Diabetic kidney disease (DKD) and primary glomerular disease (PGD) are the main causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD). This study was conducted to compare the characteristics of ambulatory blood-pressure monitoring (ABPM) and its relationship with target-organ damage (TOD) in patients with DKD and PGD matched by propensity score. The assessment of TOD included macroalbuminuria, left ventricular hypertrophy (LVH) and macrovascular disease. Propensity-score weighting (PSW) was used in stratified analysis. Results: Patients with DKD had a higher prevalence of abnormal blood-pressure patterns such as reversed dipper pattern, nocturnal hypertension, and sustained hypertension and had a higher prevalence of TOD than did patients with PGD. Logistic regression indicated that patients with DKD were more related to TOD than to PGD. The stratified analysis indicated that DKD patients with white-coat hypertension, masked hypertension and sustained hypertension had closer relationships with TOD compared with PGD patients. Conclusion: Patients with type 2 diabetic kidney disease had more abnormal blood-pressure patterns and were more closely related to target organ damage than were patients with primary glomerular disease. |
| first_indexed | 2024-03-11T09:57:18Z |
| format | Article |
| id | doaj.art-c60cc90aa8614b3e924c4bcb98838f92 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T09:57:18Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-c60cc90aa8614b3e924c4bcb98838f922023-11-16T15:42:21ZengMDPI AGJournal of Clinical Medicine2077-03832022-12-0112116710.3390/jcm12010167Diabetic Kidney Disease versus Primary Glomerular Disease: A Propensity Score-Matched Analysis of Association between Ambulatory Blood-Pressure Monitoring and Target-Organ DamageTiantian Yu0Shicong Song1Xiaoqiu Chen2Tanqi Lou3Jun Zhang4Hui Peng5Man Li6Cheng Wang7Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-sen University, 52 Meihua East Road, Zhuhai 519000, ChinaDivision of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-sen University, 52 Meihua East Road, Zhuhai 519000, ChinaDivision of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-sen University, 52 Meihua East Road, Zhuhai 519000, ChinaDivision of Nephrology, Department of Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, ChinaDivision of Nephrology, Department of Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, ChinaDivision of Nephrology, Department of Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, ChinaDivision of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-sen University, 52 Meihua East Road, Zhuhai 519000, ChinaDivision of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-sen University, 52 Meihua East Road, Zhuhai 519000, ChinaDiabetic kidney disease (DKD) and primary glomerular disease (PGD) are the main causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD). This study was conducted to compare the characteristics of ambulatory blood-pressure monitoring (ABPM) and its relationship with target-organ damage (TOD) in patients with DKD and PGD matched by propensity score. The assessment of TOD included macroalbuminuria, left ventricular hypertrophy (LVH) and macrovascular disease. Propensity-score weighting (PSW) was used in stratified analysis. Results: Patients with DKD had a higher prevalence of abnormal blood-pressure patterns such as reversed dipper pattern, nocturnal hypertension, and sustained hypertension and had a higher prevalence of TOD than did patients with PGD. Logistic regression indicated that patients with DKD were more related to TOD than to PGD. The stratified analysis indicated that DKD patients with white-coat hypertension, masked hypertension and sustained hypertension had closer relationships with TOD compared with PGD patients. Conclusion: Patients with type 2 diabetic kidney disease had more abnormal blood-pressure patterns and were more closely related to target organ damage than were patients with primary glomerular disease.https://www.mdpi.com/2077-0383/12/1/167diabetic kidney diseaseprimary glomerular diseaseambulatory blood-pressure monitoringtarget-organ damagepropensity-score matching |
| spellingShingle | Tiantian Yu Shicong Song Xiaoqiu Chen Tanqi Lou Jun Zhang Hui Peng Man Li Cheng Wang Diabetic Kidney Disease versus Primary Glomerular Disease: A Propensity Score-Matched Analysis of Association between Ambulatory Blood-Pressure Monitoring and Target-Organ Damage Journal of Clinical Medicine diabetic kidney disease primary glomerular disease ambulatory blood-pressure monitoring target-organ damage propensity-score matching |
| title | Diabetic Kidney Disease versus Primary Glomerular Disease: A Propensity Score-Matched Analysis of Association between Ambulatory Blood-Pressure Monitoring and Target-Organ Damage |
| title_full | Diabetic Kidney Disease versus Primary Glomerular Disease: A Propensity Score-Matched Analysis of Association between Ambulatory Blood-Pressure Monitoring and Target-Organ Damage |
| title_fullStr | Diabetic Kidney Disease versus Primary Glomerular Disease: A Propensity Score-Matched Analysis of Association between Ambulatory Blood-Pressure Monitoring and Target-Organ Damage |
| title_full_unstemmed | Diabetic Kidney Disease versus Primary Glomerular Disease: A Propensity Score-Matched Analysis of Association between Ambulatory Blood-Pressure Monitoring and Target-Organ Damage |
| title_short | Diabetic Kidney Disease versus Primary Glomerular Disease: A Propensity Score-Matched Analysis of Association between Ambulatory Blood-Pressure Monitoring and Target-Organ Damage |
| title_sort | diabetic kidney disease versus primary glomerular disease a propensity score matched analysis of association between ambulatory blood pressure monitoring and target organ damage |
| topic | diabetic kidney disease primary glomerular disease ambulatory blood-pressure monitoring target-organ damage propensity-score matching |
| url | https://www.mdpi.com/2077-0383/12/1/167 |
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