Natural Compounds as Therapeutic Agents: The Case of Human Topoisomerase IB
Natural products are widely used as source for drugs development. An interesting example is represented by natural drugs developed against human topoisomerase IB, a ubiquitous enzyme involved in many cellular processes where several topological problems occur due the formation of supercoiled DNA. Hu...
Main Authors: | Alessio Ottaviani, Federico Iacovelli, Paola Fiorani, Alessandro Desideri |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/8/4138 |
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