Frequent down regulation of the tumor suppressor gene a20 in multiple myeloma.

Frequent down regulation of the tumor suppressor gene a20 in multiple myeloma.

Multiple myeloma (MM) is a malignant clonal expansion of plasma cells in the bone marrow and belongs to the mature B-cell neoplams. The pathogenesis of MM is associated with constitutive NF-κB activation. However, genetic alterations causing constitutive NF-κB activation are still incompletely under...

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Main Authors: Katharina Troppan, Sybille Hofer, Kerstin Wenzl, Markus Lassnig, Beata Pursche, Elisabeth Steinbauer, Marco Wiltgen, Barbara Zulus, Wilfried Renner, Christine Beham-Schmid, Alexander Deutsch, Peter Neumeister
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4391781?pdf=render

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