Venous Thromboembolism following Two Doses of COVID-19 mRNA Vaccines in the US Population, 2020–2022
The COVID-19 mRNA vaccine is one of the most effective strategies used to fight against COVID-19. Recently, venous thromboembolism (VTE) events after COVID-19 mRNA vaccination have been reported in various research. Such a concern may hamper the ongoing COVID-19 vaccination campaign. Based on the US...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/10/8/1317 |
| _version_ | 1797407529783787520 |
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| author | Daoyuan Lai Yan Dora Zhang Junfeng Lu |
| author_facet | Daoyuan Lai Yan Dora Zhang Junfeng Lu |
| author_sort | Daoyuan Lai |
| collection | DOAJ |
| description | The COVID-19 mRNA vaccine is one of the most effective strategies used to fight against COVID-19. Recently, venous thromboembolism (VTE) events after COVID-19 mRNA vaccination have been reported in various research. Such a concern may hamper the ongoing COVID-19 vaccination campaign. Based on the US Vaccine Adverse Event Reporting System data, this modified self-controlled case series study investigated the association of COVID-19 mRNA vaccination with VTE events among US adults. We found the VTE incidence rate in the recommended dose interval does not change significantly after receiving COVID-19 mRNA vaccines. This conclusion still holds if the analysis is stratified by age and gender. The VTE onset may not be significantly associated with COVID-19 mRNA vaccination. |
| first_indexed | 2024-03-09T03:43:48Z |
| format | Article |
| id | doaj.art-c6116611043445f98e7e6e90513ea608 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-09T03:43:48Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-c6116611043445f98e7e6e90513ea6082023-12-03T14:37:39ZengMDPI AGVaccines2076-393X2022-08-01108131710.3390/vaccines10081317Venous Thromboembolism following Two Doses of COVID-19 mRNA Vaccines in the US Population, 2020–2022Daoyuan Lai0Yan Dora Zhang1Junfeng Lu2Department of Statistics and Actuarial Science, Faculty of Science, The University of Hong Kong, Hong Kong 999077, ChinaDepartment of Statistics and Actuarial Science, Faculty of Science, The University of Hong Kong, Hong Kong 999077, ChinaFirst Department of Liver Disease, Beijing You’An Hospital, Capital Medical University, Beijing 100069, ChinaThe COVID-19 mRNA vaccine is one of the most effective strategies used to fight against COVID-19. Recently, venous thromboembolism (VTE) events after COVID-19 mRNA vaccination have been reported in various research. Such a concern may hamper the ongoing COVID-19 vaccination campaign. Based on the US Vaccine Adverse Event Reporting System data, this modified self-controlled case series study investigated the association of COVID-19 mRNA vaccination with VTE events among US adults. We found the VTE incidence rate in the recommended dose interval does not change significantly after receiving COVID-19 mRNA vaccines. This conclusion still holds if the analysis is stratified by age and gender. The VTE onset may not be significantly associated with COVID-19 mRNA vaccination.https://www.mdpi.com/2076-393X/10/8/1317adverse drug reactionCOVID-19 mRNA vaccinesvenous thromboembolismVAERS |
| spellingShingle | Daoyuan Lai Yan Dora Zhang Junfeng Lu Venous Thromboembolism following Two Doses of COVID-19 mRNA Vaccines in the US Population, 2020–2022 Vaccines adverse drug reaction COVID-19 mRNA vaccines venous thromboembolism VAERS |
| title | Venous Thromboembolism following Two Doses of COVID-19 mRNA Vaccines in the US Population, 2020–2022 |
| title_full | Venous Thromboembolism following Two Doses of COVID-19 mRNA Vaccines in the US Population, 2020–2022 |
| title_fullStr | Venous Thromboembolism following Two Doses of COVID-19 mRNA Vaccines in the US Population, 2020–2022 |
| title_full_unstemmed | Venous Thromboembolism following Two Doses of COVID-19 mRNA Vaccines in the US Population, 2020–2022 |
| title_short | Venous Thromboembolism following Two Doses of COVID-19 mRNA Vaccines in the US Population, 2020–2022 |
| title_sort | venous thromboembolism following two doses of covid 19 mrna vaccines in the us population 2020 2022 |
| topic | adverse drug reaction COVID-19 mRNA vaccines venous thromboembolism VAERS |
| url | https://www.mdpi.com/2076-393X/10/8/1317 |
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