Endocrine disrupting chemicals and male fertility: from physiological to molecular effects
The deleterious effects of chemical or non-chemical endocrine disruptors (EDs) on male fertility potential is well documented but still not fully elucidated. For example, the detection of industrial chemicals’ metabolites in seminal plasma and follicular fluid can affect efficiency of the gametogene...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1232646/full |
| _version_ | 1797662479832055808 |
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| author | Marwa Lahimer Marwa Lahimer Marwa Lahimer Maria Abou Diwan Debbie Montjean Rosalie Cabry Rosalie Cabry Véronique Bach Mounir Ajina Habib Ben Ali Moncef Benkhalifa Moncef Benkhalifa Hafida Khorsi-Cauet Hafida Khorsi-Cauet |
| author_facet | Marwa Lahimer Marwa Lahimer Marwa Lahimer Maria Abou Diwan Debbie Montjean Rosalie Cabry Rosalie Cabry Véronique Bach Mounir Ajina Habib Ben Ali Moncef Benkhalifa Moncef Benkhalifa Hafida Khorsi-Cauet Hafida Khorsi-Cauet |
| author_sort | Marwa Lahimer |
| collection | DOAJ |
| description | The deleterious effects of chemical or non-chemical endocrine disruptors (EDs) on male fertility potential is well documented but still not fully elucidated. For example, the detection of industrial chemicals’ metabolites in seminal plasma and follicular fluid can affect efficiency of the gametogenesis, the maturation and competency of gametes and has guided scientists to hypothesize that endocrine disrupting chemicals (EDCs) may disrupt hormonal homoeostasis by leading to a wide range of hormonal control impairments. The effects of EDCs exposure on reproductive health are highly dependent on factors including the type of EDCs, the duration of exposure, individual susceptibility, and the presence of other co-factors. Research and scientists continue to study these complex interactions. The aim of this review is to summarize the literature to better understand the potential reproductive health risks of EDCs in France. |
| first_indexed | 2024-03-11T19:00:47Z |
| format | Article |
| id | doaj.art-c612a6dcecfa4942bc6ba7b128af571d |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-03-11T19:00:47Z |
| publishDate | 2023-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-c612a6dcecfa4942bc6ba7b128af571d2023-10-10T13:18:15ZengFrontiers Media S.A.Frontiers in Public Health2296-25652023-10-011110.3389/fpubh.2023.12326461232646Endocrine disrupting chemicals and male fertility: from physiological to molecular effectsMarwa Lahimer0Marwa Lahimer1Marwa Lahimer2Maria Abou Diwan3Debbie Montjean4Rosalie Cabry5Rosalie Cabry6Véronique Bach7Mounir Ajina8Habib Ben Ali9Moncef Benkhalifa10Moncef Benkhalifa11Hafida Khorsi-Cauet12Hafida Khorsi-Cauet13ART and Reproductive Biology Laboratory, University Hospital and School of Medicine, CHU Sud, Amiens, FrancePERITOX-(UMR-I 01), UPJV/INERIS, UPJV, CURS, Chemin du Thil, Amiens, FranceExercise Physiology and Physiopathology: from Integrated to Molecular “Biology, Medicine and Health” (Code: LR19ES09), Sousse, TunisiaPERITOX-(UMR-I 01), UPJV/INERIS, UPJV, CURS, Chemin du Thil, Amiens, FranceFertilys, Centres de Fertilité, Laval and Brossard, QC, CanadaART and Reproductive Biology Laboratory, University Hospital and School of Medicine, CHU Sud, Amiens, FrancePERITOX-(UMR-I 01), UPJV/INERIS, UPJV, CURS, Chemin du Thil, Amiens, FrancePERITOX-(UMR-I 01), UPJV/INERIS, UPJV, CURS, Chemin du Thil, Amiens, FranceService of Reproductive Medicine, University Hospital Farhat Hached, Sousse, TunisiaLaboratory Histology Embryology, Faculty of Medicine Sousse, University of Sousse, Sousse, TunisiaART and Reproductive Biology Laboratory, University Hospital and School of Medicine, CHU Sud, Amiens, FrancePERITOX-(UMR-I 01), UPJV/INERIS, UPJV, CURS, Chemin du Thil, Amiens, FranceART and Reproductive Biology Laboratory, University Hospital and School of Medicine, CHU Sud, Amiens, FrancePERITOX-(UMR-I 01), UPJV/INERIS, UPJV, CURS, Chemin du Thil, Amiens, FranceThe deleterious effects of chemical or non-chemical endocrine disruptors (EDs) on male fertility potential is well documented but still not fully elucidated. For example, the detection of industrial chemicals’ metabolites in seminal plasma and follicular fluid can affect efficiency of the gametogenesis, the maturation and competency of gametes and has guided scientists to hypothesize that endocrine disrupting chemicals (EDCs) may disrupt hormonal homoeostasis by leading to a wide range of hormonal control impairments. The effects of EDCs exposure on reproductive health are highly dependent on factors including the type of EDCs, the duration of exposure, individual susceptibility, and the presence of other co-factors. Research and scientists continue to study these complex interactions. The aim of this review is to summarize the literature to better understand the potential reproductive health risks of EDCs in France.https://www.frontiersin.org/articles/10.3389/fpubh.2023.1232646/fullendocrine disrupting chemicalspesticidesspermatogenesissperm characteristicshormonal disordersepigenetics modification |
| spellingShingle | Marwa Lahimer Marwa Lahimer Marwa Lahimer Maria Abou Diwan Debbie Montjean Rosalie Cabry Rosalie Cabry Véronique Bach Mounir Ajina Habib Ben Ali Moncef Benkhalifa Moncef Benkhalifa Hafida Khorsi-Cauet Hafida Khorsi-Cauet Endocrine disrupting chemicals and male fertility: from physiological to molecular effects Frontiers in Public Health endocrine disrupting chemicals pesticides spermatogenesis sperm characteristics hormonal disorders epigenetics modification |
| title | Endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
| title_full | Endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
| title_fullStr | Endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
| title_full_unstemmed | Endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
| title_short | Endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
| title_sort | endocrine disrupting chemicals and male fertility from physiological to molecular effects |
| topic | endocrine disrupting chemicals pesticides spermatogenesis sperm characteristics hormonal disorders epigenetics modification |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1232646/full |
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