Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis.

Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis.

BACKGROUND: Leishmania major cutaneous leishmaniasis is an infectious zoonotic disease. It is produced by a digenetic parasite, which resides in the phagolysosomal compartment of different mammalian macrophage populations. There is an urgent need to develop new therapies (drugs) against this neglect...

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Bibliographic Details
Main Authors: Estefania Calvo-Álvarez, Nestor Adrian Guerrero, Raquel Alvarez-Velilla, Christopher Fernández Prada, Jose María Requena, Carmen Punzón, Miguel Ángel Llamas, Francisco J Arévalo, Luis Rivas, Manuel Fresno, Yolanda Pérez-Pertejo, Rafael Balaña-Fouce, Rosa M Reguera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3510153?pdf=render

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