The pathological mechanisms of circRNAs in mediating intervertebral disc degeneration

The pathological mechanisms of circRNAs in mediating intervertebral disc degeneration

Lower back pain (LBP) is a worldwide health problem associated with significant economic and social burden. Intervertebral disc degeneration (IVDD) is a leading cause of LBP. Several studies show that the death of nucleus pulposus cells (NPCs), abnormal metabolism of the extracellular matrix (ECM),...

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Bibliographic Details
Main Authors: Yongjin Li, Suzhe Zhou, Xinli Hu, Shibao Lu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-12-01
Series:Non-coding RNA Research
Subjects:
Intervertebral disc degeneration
Nucleus pulposus cells
Circular RNAs
Extracellular matrix
Inflammatory response
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054023000604

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